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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRP1B All Species: 17.58
Human Site: S4529 Identified Species: 38.67
UniProt: Q9NZR2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZR2 NP_061027.2 4599 515498 S4529 R Y I G G G P S A F K L P H T
Chimpanzee Pan troglodytes XP_515817 4636 518955 S4566 R Y I G G G P S A F K L P H T
Rhesus Macaque Macaca mulatta XP_001117994 4592 514768 S4522 R Y I A G G P S A F K L P H T
Dog Lupus familis XP_533343 4492 503712 S4422 R Y I G G G S S A F K L P H T
Cat Felis silvestris
Mouse Mus musculus Q9JI18 4599 513616 S4529 R Y I G G G S S A F K L P H T
Rat Rattus norvegicus P98158 4660 519258 P4595 W N I F K R K P K Q T T N F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P98157 4543 507114 K4473 E I G N P T Y K M Y E G E P D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920039 4500 501034 Y4430 G N P S Y N M Y E V D H D N H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788284 4699 524910 A4631 V E I M L T N A M Y R G D A D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q04833 4753 526406 P4687 S A M S P N R P S T S A A S S
Sea Urchin Strong. purpuratus XP_787118 4478 501013 E4413 Y S R Q V N E E E E G A D G M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 98.1 94.6 N.A. 91.6 35.2 N.A. N.A. 61.4 N.A. 69.4 N.A. 34.6 N.A. 31.1 41.4
Protein Similarity: 100 98.9 98.8 96.1 N.A. 96.2 51.7 N.A. N.A. 75.5 N.A. 82.2 N.A. 51.9 N.A. 48.6 58.6
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 6.6 N.A. N.A. 0 N.A. 0 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 6.6 N.A. N.A. 13.3 N.A. 6.6 N.A. 26.6 N.A. 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 0 0 10 46 0 0 19 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 28 0 19 % D
% Glu: 10 10 0 0 0 0 10 10 19 10 10 0 10 0 10 % E
% Phe: 0 0 0 10 0 0 0 0 0 46 0 0 0 10 0 % F
% Gly: 10 0 10 37 46 46 0 0 0 0 10 19 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 46 10 % H
% Ile: 0 10 64 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 10 10 10 0 46 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 46 0 0 0 % L
% Met: 0 0 10 10 0 0 10 0 19 0 0 0 0 0 10 % M
% Asn: 0 19 0 10 0 28 10 0 0 0 0 0 10 10 0 % N
% Pro: 0 0 10 0 19 0 28 19 0 0 0 0 46 10 0 % P
% Gln: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 46 0 10 0 0 10 10 0 0 0 10 0 0 0 0 % R
% Ser: 10 10 0 19 0 0 19 46 10 0 10 0 0 10 10 % S
% Thr: 0 0 0 0 0 19 0 0 0 10 10 10 0 0 46 % T
% Val: 10 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 46 0 0 10 0 10 10 0 19 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _