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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1B
All Species:
21.52
Human Site:
S4578
Identified Species:
47.33
UniProt:
Q9NZR2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZR2
NP_061027.2
4599
515498
S4578
N
C
R
N
S
L
G
S
V
D
E
R
K
E
L
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
S4615
N
C
R
N
S
L
G
S
V
D
E
R
K
E
L
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
S4571
N
C
R
N
S
L
G
S
V
D
E
R
K
E
L
Dog
Lupus familis
XP_533343
4492
503712
S4471
N
C
R
N
S
L
G
S
V
D
E
R
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI18
4599
513616
S4578
N
C
R
N
S
L
A
S
V
D
E
R
K
E
L
Rat
Rattus norvegicus
P98158
4660
519258
E4644
T
P
G
Y
T
A
T
E
D
T
F
K
D
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
S4522
S
S
R
N
S
L
A
S
T
D
E
K
R
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920039
4500
501034
N4479
N
C
R
K
P
V
I
N
I
D
E
R
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788284
4699
524910
D4680
I
T
H
S
T
A
P
D
E
R
K
G
L
L
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
P4736
P
K
K
E
K
A
D
P
L
R
V
D
N
P
L
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
P4462
N
K
K
F
V
D
L
P
Q
R
D
T
E
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
98.1
94.6
N.A.
91.6
35.2
N.A.
N.A.
61.4
N.A.
69.4
N.A.
34.6
N.A.
31.1
41.4
Protein Similarity:
100
98.9
98.8
96.1
N.A.
96.2
51.7
N.A.
N.A.
75.5
N.A.
82.2
N.A.
51.9
N.A.
48.6
58.6
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
N.A.
60
N.A.
53.3
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
N.A.
80
N.A.
80
N.A.
20
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
28
19
0
0
0
0
0
0
0
10
% A
% Cys:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
10
10
64
10
10
10
0
0
% D
% Glu:
0
0
0
10
0
0
0
10
10
0
64
0
10
64
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
37
0
0
0
0
10
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
0
19
19
10
10
0
0
0
0
0
10
19
46
0
0
% K
% Leu:
0
0
0
0
0
55
10
0
10
0
0
0
10
10
82
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
64
0
0
55
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
10
10
0
0
10
0
10
19
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% Q
% Arg:
0
0
64
0
0
0
0
0
0
28
0
55
19
10
0
% R
% Ser:
10
10
0
10
55
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
10
10
0
0
19
0
10
0
10
10
0
10
0
10
0
% T
% Val:
0
0
0
0
10
10
0
0
46
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _