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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRP1B
All Species:
16.06
Human Site:
Y390
Identified Species:
35.33
UniProt:
Q9NZR2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZR2
NP_061027.2
4599
515498
Y390
L
V
Y
W
V
D
L
Y
L
D
Y
V
G
V
V
Chimpanzee
Pan troglodytes
XP_515817
4636
518955
Y427
L
V
Y
W
V
D
L
Y
L
D
Y
V
G
V
V
Rhesus Macaque
Macaca mulatta
XP_001117994
4592
514768
Y383
L
V
Y
W
V
D
L
Y
L
D
Y
V
G
V
V
Dog
Lupus familis
XP_533343
4492
503712
Y373
H
A
C
E
V
D
P
Y
G
M
P
G
G
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI18
4599
513616
Y390
L
V
Y
W
V
D
L
Y
L
D
Y
V
G
V
V
Rat
Rattus norvegicus
P98158
4660
519258
Y577
V
Y
W
V
D
S
R
Y
D
Y
I
E
T
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P98157
4543
507114
V395
A
Y
L
D
Y
I
E
V
V
D
Y
E
G
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920039
4500
501034
I369
S
S
G
T
V
V
D
I
L
R
I
N
R
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788284
4699
524910
V455
I
D
I
Y
K
D
E
V
N
R
V
D
Y
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q04833
4753
526406
I582
K
V
D
R
L
E
S
I
D
Y
Q
G
N
D
R
Sea Urchin
Strong. purpuratus
XP_787118
4478
501013
Q389
R
I
Y
F
A
D
T
Q
L
E
M
V
Q
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
98.1
94.6
N.A.
91.6
35.2
N.A.
N.A.
61.4
N.A.
69.4
N.A.
34.6
N.A.
31.1
41.4
Protein Similarity:
100
98.9
98.8
96.1
N.A.
96.2
51.7
N.A.
N.A.
75.5
N.A.
82.2
N.A.
51.9
N.A.
48.6
58.6
P-Site Identity:
100
100
100
26.6
N.A.
100
13.3
N.A.
N.A.
20
N.A.
13.3
N.A.
6.6
N.A.
6.6
26.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
26.6
N.A.
N.A.
26.6
N.A.
13.3
N.A.
20
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
10
10
10
64
10
0
19
46
0
10
0
10
0
% D
% Glu:
0
0
0
10
0
10
19
0
0
10
0
19
0
10
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
19
55
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
10
0
0
10
0
19
0
0
19
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
37
0
10
0
10
0
37
0
55
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
19
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% Q
% Arg:
10
0
0
10
0
0
10
0
0
19
0
0
10
0
10
% R
% Ser:
10
10
0
0
0
10
10
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
10
0
0
10
0
0
0
0
0
10
10
10
% T
% Val:
10
46
0
10
55
10
0
19
10
0
10
46
0
46
37
% V
% Trp:
0
0
10
37
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
46
10
10
0
0
55
0
19
46
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _