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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BFAR All Species: 25.76
Human Site: S169 Identified Species: 62.96
UniProt: Q9NZS9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZS9 NP_057645.1 450 52738 S169 Y H W S S R E S E H D L L V H
Chimpanzee Pan troglodytes XP_001148011 450 52744 S169 Y H W S S K E S E H D L L V H
Rhesus Macaque Macaca mulatta XP_001107892 450 52805 S169 Y H W S S R E S E H D L L V H
Dog Lupus familis XP_547118 450 52548 S169 Y H W S S R E S E H D L L V H
Cat Felis silvestris
Mouse Mus musculus Q8R079 450 52950 S169 Y H W R S R E S E H G L L V H
Rat Rattus norvegicus Q5PQN2 450 53006 S169 Y H W R S R E S E H G L L V H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516855 331 37501 D74 S H E E E E P D T S V S G Q I
Chicken Gallus gallus XP_414737 437 51603 F157 Y H W S S R E F E D D L L V H
Frog Xenopus laevis NP_001088347 448 52481 S165 Y H W S S R D S E Q D L L V H
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784327 488 56535 Q216 I L L N W N R Q D S E M L V Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.2 92.8 N.A. 90 90.2 N.A. 52 79.5 75.7 N.A. N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 99.7 99.5 96.8 N.A. 94.8 94.8 N.A. 58.2 87.5 85.7 N.A. N.A. N.A. N.A. N.A. 57.1
P-Site Identity: 100 93.3 100 100 N.A. 86.6 86.6 N.A. 6.6 86.6 86.6 N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 6.6 86.6 93.3 N.A. N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 10 10 10 60 0 0 0 0 % D
% Glu: 0 0 10 10 10 10 70 0 80 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 20 0 10 0 0 % G
% His: 0 90 0 0 0 0 0 0 0 60 0 0 0 0 80 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 10 0 0 0 0 0 0 0 0 80 90 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 10 0 0 0 10 0 % Q
% Arg: 0 0 0 20 0 70 10 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 60 80 0 0 70 0 20 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 0 90 0 % V
% Trp: 0 0 80 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 80 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _