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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BFAR All Species: 21.82
Human Site: S22 Identified Species: 53.33
UniProt: Q9NZS9 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZS9 NP_057645.1 450 52738 S22 E R D E P L K S T G P Q I S V
Chimpanzee Pan troglodytes XP_001148011 450 52744 S22 E R D E P L K S T G P Q I S V
Rhesus Macaque Macaca mulatta XP_001107892 450 52805 S22 E K D E P L K S T G P Q I S V
Dog Lupus familis XP_547118 450 52548 S22 D N D D P L K S T S P Q I S V
Cat Felis silvestris
Mouse Mus musculus Q8R079 450 52950 S22 E E E H P V R S S G P Q I S V
Rat Rattus norvegicus Q5PQN2 450 53006 S22 E E D H P V R S S G P Q I S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516855 331 37501
Chicken Gallus gallus XP_414737 437 51603 H24 S V S E F L C H C C Y D I L V
Frog Xenopus laevis NP_001088347 448 52481 R22 I A T A K L D R K I S V S E F
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784327 488 56535 Y70 E S P D D A L Y S E V S S L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.2 92.8 N.A. 90 90.2 N.A. 52 79.5 75.7 N.A. N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 99.7 99.5 96.8 N.A. 94.8 94.8 N.A. 58.2 87.5 85.7 N.A. N.A. N.A. N.A. N.A. 57.1
P-Site Identity: 100 100 93.3 73.3 N.A. 60 66.6 N.A. 0 26.6 6.6 N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. 0 26.6 6.6 N.A. N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % C
% Asp: 10 0 50 20 10 0 10 0 0 0 0 10 0 0 10 % D
% Glu: 60 20 10 40 0 0 0 0 0 10 0 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % G
% His: 0 0 0 20 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 10 0 0 70 0 0 % I
% Lys: 0 10 0 0 10 0 40 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 60 10 0 0 0 0 0 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 60 0 0 0 0 0 60 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 60 0 0 0 % Q
% Arg: 0 20 0 0 0 0 20 10 0 0 0 0 0 0 0 % R
% Ser: 10 10 10 0 0 0 0 60 30 10 10 10 20 60 0 % S
% Thr: 0 0 10 0 0 0 0 0 40 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 20 0 0 0 0 10 10 0 0 70 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _