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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BFAR All Species: 22.42
Human Site: S28 Identified Species: 54.81
UniProt: Q9NZS9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZS9 NP_057645.1 450 52738 S28 K S T G P Q I S V S E F S C H
Chimpanzee Pan troglodytes XP_001148011 450 52744 S28 K S T G P Q I S V S E F S C H
Rhesus Macaque Macaca mulatta XP_001107892 450 52805 S28 K S T G P Q I S V S E F S C H
Dog Lupus familis XP_547118 450 52548 S28 K S T S P Q I S V S E F S C H
Cat Felis silvestris
Mouse Mus musculus Q8R079 450 52950 S28 R S S G P Q I S V S E F S C H
Rat Rattus norvegicus Q5PQN2 450 53006 S28 R S S G P Q I S V S E F S C H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516855 331 37501
Chicken Gallus gallus XP_414737 437 51603 L30 C H C C Y D I L V N P T T L N
Frog Xenopus laevis NP_001088347 448 52481 E28 D R K I S V S E F S C H C C Y
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784327 488 56535 L76 L Y S E V S S L D S N F S C A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.2 92.8 N.A. 90 90.2 N.A. 52 79.5 75.7 N.A. N.A. N.A. N.A. N.A. 38.1
Protein Similarity: 100 99.7 99.5 96.8 N.A. 94.8 94.8 N.A. 58.2 87.5 85.7 N.A. N.A. N.A. N.A. N.A. 57.1
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 0 13.3 13.3 N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 0 33.3 20 N.A. N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 10 0 10 10 0 0 0 0 0 0 10 0 10 80 0 % C
% Asp: 10 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 10 0 0 60 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 70 0 0 0 % F
% Gly: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 60 % H
% Ile: 0 0 0 10 0 0 70 0 0 0 0 0 0 0 0 % I
% Lys: 40 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 20 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 10 % N
% Pro: 0 0 0 0 60 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % Q
% Arg: 20 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 60 30 10 10 10 20 60 0 80 0 0 70 0 0 % S
% Thr: 0 0 40 0 0 0 0 0 0 0 0 10 10 0 0 % T
% Val: 0 0 0 0 10 10 0 0 70 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _