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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OGFR All Species: 7.88
Human Site: S537 Identified Species: 19.26
UniProt: Q9NZT2 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZT2 NP_031372.2 677 73325 S537 A G D E P A E S P S E T P G P
Chimpanzee Pan troglodytes XP_514771 616 67348 S536 S G H K L V E S P S E T P G P
Rhesus Macaque Macaca mulatta XP_001087181 599 65749 S519 P K E G T P G S P S E T P G P
Dog Lupus familis XP_543089 518 57103 V445 E V R K R R K V D Q G P G G G
Cat Felis silvestris
Mouse Mus musculus Q99PG2 633 70661 P507 S Q V G P E D P K G Q V E P E
Rat Rattus norvegicus Q9QXY4 580 64709 D497 N S Q V G L E D P N S Q V G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506222 648 73731 R523 S S S S R I I R P D L Q S G S
Chicken Gallus gallus XP_425708 638 72265 T536 V L P S T A Q T S P L S D G M
Frog Xenopus laevis NP_001079776 330 39069 C257 G P R D I L S C R A A R S S E
Zebra Danio Brachydanio rerio XP_695983 464 53369 D391 T D P Q D Q M D S P V R A G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.5 83.5 51.9 N.A. 55.3 53.4 N.A. 37.6 34.2 27.6 34.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.1 85.5 56.1 N.A. 65.1 63.6 N.A. 51.7 51.2 35 44.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 66.6 53.3 6.6 N.A. 6.6 26.6 N.A. 13.3 13.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 80 60 20 N.A. 26.6 33.3 N.A. 20 33.3 13.3 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 20 0 0 0 10 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 10 10 10 10 0 10 20 10 10 0 0 10 0 0 % D
% Glu: 10 0 10 10 0 10 30 0 0 0 30 0 10 0 30 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 20 0 20 10 0 10 0 0 10 10 0 10 80 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 20 0 0 10 0 10 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 10 20 0 0 0 0 20 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % M
% Asn: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 10 20 0 20 10 0 10 50 20 0 10 30 10 40 % P
% Gln: 0 10 10 10 0 10 10 0 0 10 10 20 0 0 0 % Q
% Arg: 0 0 20 0 20 10 0 10 10 0 0 20 0 0 0 % R
% Ser: 30 20 10 20 0 0 10 30 20 30 10 10 20 10 10 % S
% Thr: 10 0 0 0 20 0 0 10 0 0 0 30 0 0 0 % T
% Val: 10 10 10 10 0 10 0 10 0 0 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _