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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPN1 All Species: 1.52
Human Site: S78 Identified Species: 8.33
UniProt: Q9NZV5 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZV5 NP_065184.2 590 65827 S78 D G L F L F S S L D T D G D M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_855040 375 42523
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus XP_002729597 509 57699 V19 E Q E S A L K V L G T D G L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001108444 530 59577 A39 A A R Q Q E L A L K S L G S E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q3Y4E2 557 62455 Y54 I G V C I K Y Y L D I Q F V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 58.4 N.A. N.A. 77.6 N.A. N.A. 70.1 N.A. 62.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 60.8 N.A. N.A. 81.6 N.A. N.A. 80.8 N.A. 72.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 0 N.A. N.A. 26.6 N.A. N.A. 13.3 N.A. 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 0 N.A. N.A. 33.3 N.A. N.A. 26.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 20 0 0 20 0 0 20 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 0 0 0 0 0 0 0 0 40 0 40 0 20 0 % D
% Glu: 20 0 20 0 0 20 0 0 0 0 0 0 0 0 20 % E
% Phe: 0 0 0 20 0 20 0 0 0 0 0 0 20 0 20 % F
% Gly: 0 40 0 0 0 0 0 0 0 20 0 0 60 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 0 0 0 20 0 0 0 0 0 20 0 0 0 0 % I
% Lys: 0 0 0 0 0 20 20 0 0 20 0 0 0 0 20 % K
% Leu: 0 0 20 0 20 20 20 0 80 0 0 20 0 20 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 20 0 20 20 0 0 0 0 0 0 20 0 0 0 % Q
% Arg: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 20 0 0 20 20 0 0 20 0 0 20 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 40 0 0 0 0 % T
% Val: 0 0 20 0 0 0 0 20 0 0 0 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 20 20 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _