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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCND2 All Species: 14.55
Human Site: S454 Identified Species: 32
UniProt: Q9NZV8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZV8 NP_036413.1 630 70537 S454 S K R N G L L S N Q L Q S S E
Chimpanzee Pan troglodytes XP_527864 649 72708 S473 F V S K S G S S F E T Q H H H
Rhesus Macaque Macaca mulatta XP_001082011 651 73020 F475 V S K S G S S F E T Q H H H L
Dog Lupus familis XP_852736 630 70424 T454 S K R N G L L T N Q L Q S S E
Cat Felis silvestris
Mouse Mus musculus Q9Z0V2 630 70558 S454 S K R N G L L S N Q L Q S S E
Rat Rattus norvegicus Q63881 630 70530 S454 S K R N G L L S N Q L Q S S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508294 638 71325 A453 R N G L L N E A L E L M G S T
Chicken Gallus gallus NP_989610 632 70965 Q456 R N G L L S N Q L Q Q S S S E
Frog Xenopus laevis P22739 499 56683 R326 Q T L N A S M R E L G L L I F
Zebra Danio Brachydanio rerio NP_001076336 630 70886 M455 R N G M L V D M E E E A S K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17971 490 55900 L317 L R I L G Y T L K S C A S E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 96 97.9 N.A. 99 99 N.A. 76.4 93.5 29 80.7 N.A. 58.2 N.A. N.A. N.A.
Protein Similarity: 100 97 96.4 99.2 N.A. 99.5 99.5 N.A. 87.4 96.8 44.2 88.7 N.A. 68.5 N.A. N.A. N.A.
P-Site Identity: 100 13.3 6.6 93.3 N.A. 100 100 N.A. 13.3 26.6 6.6 13.3 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 20 20 100 N.A. 100 100 N.A. 26.6 26.6 13.3 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 0 0 0 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 28 28 10 0 0 10 55 % E
% Phe: 10 0 0 0 0 0 0 10 10 0 0 0 0 0 10 % F
% Gly: 0 0 28 0 55 10 0 0 0 0 10 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 19 19 10 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 37 10 10 0 0 0 0 10 0 0 0 0 10 0 % K
% Leu: 10 0 10 28 28 37 37 10 19 10 46 10 10 0 19 % L
% Met: 0 0 0 10 0 0 10 10 0 0 0 10 0 0 0 % M
% Asn: 0 28 0 46 0 10 10 0 37 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 10 0 46 19 46 0 0 0 % Q
% Arg: 28 10 37 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 37 10 10 10 10 28 19 37 0 10 0 10 64 55 0 % S
% Thr: 0 10 0 0 0 0 10 10 0 10 10 0 0 0 10 % T
% Val: 10 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _