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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP6 All Species: 28.48
Human Site: S106 Identified Species: 44.76
UniProt: Q9NZW5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZW5 NP_057531.2 540 61117 S106 V A S K C Y D S P P S S P E M
Chimpanzee Pan troglodytes XP_001159242 552 62429 S106 V A S K C Y D S P P S S P E M
Rhesus Macaque Macaca mulatta XP_001096776 582 65885 S148 V A S K C Y D S P P S S P E M
Dog Lupus familis XP_539479 540 61070 S106 V A S K C Y D S P P S S P E M
Cat Felis silvestris
Mouse Mus musculus Q9JLB0 553 62612 S106 V A S K C Y D S P P S S P E M
Rat Rattus norvegicus Q62915 909 103240 D454 V A H E V Y S D E A L R V T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507958 540 61012 S106 V A S K C Y D S P P S S P E M
Chicken Gallus gallus Q5ZJ00 468 52501 N91 M G I T L K L N D K Q S C M V
Frog Xenopus laevis NP_001084783 538 60687 S106 V A S K C Y D S P P S S P E V
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 P121 V A K K S Y D P E L P P L P D
Tiger Blowfish Takifugu rubipres P49697 467 52590 Q94 T L K L N D K Q R C S V A R I
Fruit Fly Dros. melanogaster Q24210 898 100893 E460 V A R D V Y G E E A L R V T P
Honey Bee Apis mellifera XP_391909 602 67965 P164 V V E R K E A P P S K P E P S
Nematode Worm Caenorhab. elegans P54936 961 108794 A264 L V R R M L N A D P S K R I S
Sea Urchin Strong. purpuratus XP_791632 556 63023 S120 I A T G N L G S S E F E D H T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 92.7 99.6 N.A. 95.8 30 N.A. 96.8 37.7 86.8 37.8 35.3 28.8 42.3 28.6 48.7
Protein Similarity: 100 97.8 92.7 100 N.A. 96.9 42.5 N.A. 99.2 55.3 94.8 55.9 55.5 41.8 63.7 39.9 67.9
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 100 6.6 93.3 33.3 6.6 20 13.3 13.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 100 26.6 100 33.3 13.3 20 20 40 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 74 0 0 0 0 7 7 0 14 0 0 7 0 0 % A
% Cys: 0 0 0 0 47 0 0 0 0 7 0 0 7 0 0 % C
% Asp: 0 0 0 7 0 7 54 7 14 0 0 0 7 0 7 % D
% Glu: 0 0 7 7 0 7 0 7 20 7 0 7 7 47 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 0 7 0 7 0 0 14 0 0 0 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 7 0 7 0 0 0 0 0 0 0 0 0 0 7 7 % I
% Lys: 0 0 14 54 7 7 7 0 0 7 7 7 0 0 0 % K
% Leu: 7 7 0 7 7 14 7 0 0 7 14 0 7 0 0 % L
% Met: 7 0 0 0 7 0 0 0 0 0 0 0 0 7 40 % M
% Asn: 0 0 0 0 14 0 7 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 14 54 54 7 14 47 14 14 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % Q
% Arg: 0 0 14 14 0 0 0 0 7 0 0 14 7 7 0 % R
% Ser: 0 0 47 0 7 0 7 54 7 7 60 54 0 0 14 % S
% Thr: 7 0 7 7 0 0 0 0 0 0 0 0 0 14 7 % T
% Val: 74 14 0 0 14 0 0 0 0 0 0 7 14 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _