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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP6
All Species:
21.82
Human Site:
T214
Identified Species:
34.29
UniProt:
Q9NZW5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZW5
NP_057531.2
540
61117
T214
P
S
Y
R
D
T
I
T
P
Q
Q
V
F
V
K
Chimpanzee
Pan troglodytes
XP_001159242
552
62429
S226
L
P
S
T
T
R
K
S
G
R
M
V
F
V
K
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
T256
P
S
Y
R
D
T
I
T
P
Q
Q
V
F
V
K
Dog
Lupus familis
XP_539479
540
61070
T214
P
S
Y
R
D
T
I
T
P
Q
Q
V
F
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB0
553
62612
H227
N
M
E
R
H
P
A
H
V
R
Q
V
F
V
K
Rat
Rattus norvegicus
Q62915
909
103240
S576
P
S
Y
R
T
Q
S
S
S
C
E
R
D
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
T214
P
S
Y
R
D
T
I
T
P
Q
Q
V
F
V
K
Chicken
Gallus gallus
Q5ZJ00
468
52501
K149
T
Q
G
M
V
S
I
K
V
I
P
N
Q
Q
S
Frog
Xenopus laevis
NP_001084783
538
60687
S212
P
S
Y
K
D
T
V
S
P
Q
Q
V
F
V
K
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
K227
I
K
D
E
A
Q
S
K
E
P
K
M
F
I
K
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
I151
G
V
V
T
M
K
I
I
P
R
P
Q
S
R
S
Fruit Fly
Dros. melanogaster
Q24210
898
100893
P581
P
S
Y
R
S
A
P
P
P
C
E
I
F
V
R
Honey Bee
Apis mellifera
XP_391909
602
67965
F271
G
I
E
K
N
T
Y
F
P
L
Q
C
Y
M
R
Nematode Worm
Caenorhab. elegans
P54936
961
108794
P632
P
S
Y
R
S
A
P
P
A
C
E
I
F
V
R
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
M228
P
S
Y
Q
D
C
I
M
L
P
P
I
Y
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.7
99.6
N.A.
95.8
30
N.A.
96.8
37.7
86.8
37.8
35.3
28.8
42.3
28.6
48.7
Protein Similarity:
100
97.8
92.7
100
N.A.
96.9
42.5
N.A.
99.2
55.3
94.8
55.9
55.5
41.8
63.7
39.9
67.9
P-Site Identity:
100
26.6
100
100
N.A.
40
26.6
N.A.
100
6.6
80
13.3
13.3
46.6
20
40
40
P-Site Similarity:
100
40
100
100
N.A.
46.6
40
N.A.
100
13.3
100
33.3
20
66.6
53.3
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
14
7
0
7
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
20
0
7
0
0
0
% C
% Asp:
0
0
7
0
40
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
14
7
0
0
0
0
7
0
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
67
0
0
% F
% Gly:
14
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
0
0
47
7
0
7
0
20
0
7
0
% I
% Lys:
0
7
0
14
0
7
7
14
0
0
7
0
0
0
54
% K
% Leu:
7
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% L
% Met:
0
7
0
7
7
0
0
7
0
0
7
7
0
7
0
% M
% Asn:
7
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
60
7
0
0
0
7
14
14
54
14
20
0
0
0
7
% P
% Gln:
0
7
0
7
0
14
0
0
0
34
47
7
7
7
0
% Q
% Arg:
0
0
0
54
0
7
0
0
0
20
0
7
0
7
27
% R
% Ser:
0
60
7
0
14
7
14
20
7
0
0
0
7
7
14
% S
% Thr:
7
0
0
14
14
40
0
27
0
0
0
0
0
0
0
% T
% Val:
0
7
7
0
7
0
7
0
14
0
0
47
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
60
0
0
0
7
0
0
0
0
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _