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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP6 All Species: 32.12
Human Site: Y104 Identified Species: 50.48
UniProt: Q9NZW5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZW5 NP_057531.2 540 61117 Y104 D I V A S K C Y D S P P S S P
Chimpanzee Pan troglodytes XP_001159242 552 62429 Y104 D I V A S K C Y D S P P S S P
Rhesus Macaque Macaca mulatta XP_001096776 582 65885 Y146 D I V A S K C Y D S P P S S P
Dog Lupus familis XP_539479 540 61070 Y104 D I V A S K C Y D S P P S S P
Cat Felis silvestris
Mouse Mus musculus Q9JLB0 553 62612 Y104 D I V A S K C Y D S P P S S P
Rat Rattus norvegicus Q62915 909 103240 Y452 H V V A H E V Y S D E A L R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507958 540 61012 Y104 D I V A S K C Y D S P P S S P
Chicken Gallus gallus Q5ZJ00 468 52501 K89 E P M G I T L K L N D K Q S C
Frog Xenopus laevis NP_001084783 538 60687 Y104 D I V A S K C Y D S P P S S P
Zebra Danio Brachydanio rerio Q6P0D7 576 65174 Y119 D T V A K K S Y D P E L P P L
Tiger Blowfish Takifugu rubipres P49697 467 52590 D92 G V T L K L N D K Q R C S V A
Fruit Fly Dros. melanogaster Q24210 898 100893 Y458 D V V A R D V Y G E E A L R V
Honey Bee Apis mellifera XP_391909 602 67965 E162 D A V V E R K E A P P S K P E
Nematode Worm Caenorhab. elegans P54936 961 108794 L262 R N L V R R M L N A D P S K R
Sea Urchin Strong. purpuratus XP_791632 556 63023 L118 D D I A T G N L G S S E F E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 92.7 99.6 N.A. 95.8 30 N.A. 96.8 37.7 86.8 37.8 35.3 28.8 42.3 28.6 48.7
Protein Similarity: 100 97.8 92.7 100 N.A. 96.9 42.5 N.A. 99.2 55.3 94.8 55.9 55.5 41.8 63.7 39.9 67.9
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 100 6.6 100 40 6.6 26.6 20 13.3 20
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 100 26.6 100 40 13.3 33.3 26.6 40 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 74 0 0 0 0 7 7 0 14 0 0 7 % A
% Cys: 0 0 0 0 0 0 47 0 0 0 0 7 0 0 7 % C
% Asp: 74 7 0 0 0 7 0 7 54 7 14 0 0 0 7 % D
% Glu: 7 0 0 0 7 7 0 7 0 7 20 7 0 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 7 0 0 7 0 7 0 0 14 0 0 0 0 0 0 % G
% His: 7 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 47 7 0 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 14 54 7 7 7 0 0 7 7 7 0 % K
% Leu: 0 0 7 7 0 7 7 14 7 0 0 7 14 0 7 % L
% Met: 0 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 14 0 7 7 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 14 54 54 7 14 47 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % Q
% Arg: 7 0 0 0 14 14 0 0 0 0 7 0 0 14 7 % R
% Ser: 0 0 0 0 47 0 7 0 7 54 7 7 60 54 0 % S
% Thr: 0 7 7 0 7 7 0 0 0 0 0 0 0 0 0 % T
% Val: 0 20 74 14 0 0 14 0 0 0 0 0 0 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _