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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP6
All Species:
30.3
Human Site:
Y404
Identified Species:
47.62
UniProt:
Q9NZW5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZW5
NP_057531.2
540
61117
Y404
A
D
I
K
A
G
K
Y
L
E
H
G
E
Y
E
Chimpanzee
Pan troglodytes
XP_001159242
552
62429
Y416
A
D
I
K
A
G
K
Y
L
E
H
G
E
Y
E
Rhesus Macaque
Macaca mulatta
XP_001096776
582
65885
Y446
A
D
I
K
A
G
K
Y
L
E
H
G
E
Y
E
Dog
Lupus familis
XP_539479
540
61070
Y404
A
D
I
K
A
G
K
Y
L
E
H
G
E
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB0
553
62612
Y417
A
D
I
K
A
G
K
Y
L
E
H
G
E
Y
E
Rat
Rattus norvegicus
Q62915
909
103240
F773
E
N
G
K
N
Y
Y
F
V
S
H
D
Q
M
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507958
540
61012
Y404
T
D
V
K
A
G
R
Y
L
E
H
G
E
Y
E
Chicken
Gallus gallus
Q5ZJ00
468
52501
D332
K
N
E
V
D
G
K
D
Y
Y
F
V
S
T
E
Frog
Xenopus laevis
NP_001084783
538
60687
Y402
A
D
I
K
A
G
R
Y
L
E
H
G
E
Y
E
Zebra Danio
Brachydanio rerio
Q6P0D7
576
65174
F434
A
D
I
Q
N
N
K
F
I
E
H
G
E
Y
K
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
F334
A
N
G
E
E
Y
F
F
I
S
N
E
A
M
T
Fruit Fly
Dros. melanogaster
Q24210
898
100893
H765
R
S
Y
Y
F
V
S
H
D
E
M
M
A
D
I
Honey Bee
Apis mellifera
XP_391909
602
67965
Y465
T
D
I
R
E
H
R
Y
L
E
Y
G
E
H
G
Nematode Worm
Caenorhab. elegans
P54936
961
108794
F825
V
D
G
K
H
Y
Y
F
V
T
N
E
Q
M
M
Sea Urchin
Strong. purpuratus
XP_791632
556
63023
F420
Q
D
I
L
N
H
N
F
L
E
Y
G
D
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
92.7
99.6
N.A.
95.8
30
N.A.
96.8
37.7
86.8
37.8
35.3
28.8
42.3
28.6
48.7
Protein Similarity:
100
97.8
92.7
100
N.A.
96.9
42.5
N.A.
99.2
55.3
94.8
55.9
55.5
41.8
63.7
39.9
67.9
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
80
20
93.3
60
6.6
6.6
46.6
13.3
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
93.3
26.6
100
86.6
40
13.3
73.3
40
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
0
47
0
0
0
0
0
0
0
14
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
74
0
0
7
0
0
7
7
0
0
7
7
7
0
% D
% Glu:
7
0
7
7
14
0
0
0
0
74
0
14
60
0
54
% E
% Phe:
0
0
0
0
7
0
7
34
0
0
7
0
0
7
0
% F
% Gly:
0
0
20
0
0
54
0
0
0
0
0
67
0
0
7
% G
% His:
0
0
0
0
7
14
0
7
0
0
60
0
0
7
0
% H
% Ile:
0
0
60
0
0
0
0
0
14
0
0
0
0
0
7
% I
% Lys:
7
0
0
60
0
0
47
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
7
0
0
0
0
60
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
20
14
% M
% Asn:
0
20
0
0
20
7
7
0
0
0
14
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
7
0
0
0
0
0
0
0
0
14
0
0
% Q
% Arg:
7
0
0
7
0
0
20
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
7
0
0
14
0
0
7
0
0
% S
% Thr:
14
0
0
0
0
0
0
0
0
7
0
0
0
7
7
% T
% Val:
7
0
7
7
0
7
0
0
14
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
20
14
54
7
7
14
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _