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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED11
All Species:
14.55
Human Site:
S105
Identified Species:
32
UniProt:
Q9P086
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P086
NP_001001683.1
117
13129
S105
D
Y
A
R
L
K
L
S
D
V
A
R
T
C
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001095324
117
13095
S105
D
Y
A
R
L
K
L
S
D
V
A
R
T
C
E
Dog
Lupus familis
XP_849319
191
21202
S179
D
Y
A
R
L
K
L
S
D
V
A
R
T
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8C6
117
13112
S105
D
Y
A
R
L
K
I
S
D
V
A
R
T
C
E
Rat
Rattus norvegicus
NP_001099269
135
15344
R105
D
Y
A
R
P
R
V
R
K
Q
N
W
R
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68EW7
118
13196
A105
D
Y
S
R
V
K
L
A
E
L
S
R
T
C
E
Zebra Danio
Brachydanio rerio
A3KNK7
114
12768
G100
E
Y
A
R
V
K
L
G
E
L
G
R
T
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVS4
176
19620
R101
Q
H
A
R
S
R
V
R
E
L
E
E
T
K
A
Honey Bee
Apis mellifera
XP_625097
112
12757
R98
W
H
R
L
E
H
A
R
S
R
V
N
E
L
E
Nematode Worm
Caenorhab. elegans
Q9BI74
188
20320
F109
S
S
L
H
S
E
L
F
Q
I
V
R
Y
L
D
Sea Urchin
Strong. purpuratus
XP_791981
85
9663
T73
H
R
L
E
H
A
K
T
K
L
T
E
I
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.1
61.2
N.A.
97.4
77.7
N.A.
N.A.
N.A.
76.2
65.8
N.A.
30.6
42.7
21.2
33.3
Protein Similarity:
100
N.A.
99.1
61.2
N.A.
98.2
80.7
N.A.
N.A.
N.A.
88.1
80.3
N.A.
46.5
65.8
37.7
52.9
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
26.6
N.A.
N.A.
N.A.
60
60
N.A.
20
6.6
13.3
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
46.6
N.A.
N.A.
N.A.
100
86.6
N.A.
53.3
13.3
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
64
0
0
10
10
10
0
0
37
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% C
% Asp:
55
0
0
0
0
0
0
0
37
0
0
0
0
0
10
% D
% Glu:
10
0
0
10
10
10
0
0
28
0
10
19
10
0
64
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% G
% His:
10
19
0
10
10
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
55
10
0
19
0
0
0
0
19
10
% K
% Leu:
0
0
19
10
37
0
55
0
0
37
0
0
0
28
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
10
10
0
0
0
0
10
% Q
% Arg:
0
10
10
73
0
19
0
28
0
10
0
64
10
0
0
% R
% Ser:
10
10
10
0
19
0
0
37
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
10
0
64
0
0
% T
% Val:
0
0
0
0
19
0
19
0
0
37
19
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
64
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _