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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED11 All Species: 24.85
Human Site: S36 Identified Species: 54.67
UniProt: Q9P086 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P086 NP_001001683.1 117 13129 S36 G T V I L E L S K E K T N E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095324 117 13095 S36 G T V I L E L S K E K T N E R
Dog Lupus familis XP_849319 191 21202 S110 G T V I L E L S K E K T N E R
Cat Felis silvestris
Mouse Mus musculus Q9D8C6 117 13112 S36 G T A I L E L S K E K T N E R
Rat Rattus norvegicus NP_001099269 135 15344 S36 G T A I L E L S K E K T N E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q68EW7 118 13196 S36 G N A I L E L S K E K P N E R
Zebra Danio Brachydanio rerio A3KNK7 114 12768 S31 G T I V L E L S K E K A N A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVS4 176 19620 G32 G Q A L Q E L G K E K S S Q K
Honey Bee Apis mellifera XP_625097 112 12757 F29 L Q S A G Q A F V E L S K E K
Nematode Worm Caenorhab. elegans Q9BI74 188 20320 K40 E I I Q D L G K E K Q I G K N
Sea Urchin Strong. purpuratus XP_791981 85 9663
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.1 61.2 N.A. 97.4 77.7 N.A. N.A. N.A. 76.2 65.8 N.A. 30.6 42.7 21.2 33.3
Protein Similarity: 100 N.A. 99.1 61.2 N.A. 98.2 80.7 N.A. N.A. N.A. 88.1 80.3 N.A. 46.5 65.8 37.7 52.9
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 80 66.6 N.A. 40 13.3 0 0
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. N.A. N.A. 80 80 N.A. 73.3 33.3 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 37 10 0 0 10 0 0 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 0 73 0 0 10 82 0 0 0 64 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 73 0 0 0 10 0 10 10 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 19 55 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 73 10 73 0 10 10 19 % K
% Leu: 10 0 0 10 64 10 73 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 64 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 19 0 10 10 10 0 0 0 0 10 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 % R
% Ser: 0 0 10 0 0 0 0 64 0 0 0 19 10 0 10 % S
% Thr: 0 55 0 0 0 0 0 0 0 0 0 46 0 0 0 % T
% Val: 0 0 28 10 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _