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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED11 All Species: 30
Human Site: Y84 Identified Species: 66
UniProt: Q9P086 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P086 NP_001001683.1 117 13129 Y84 Q P H E G S S Y S S R K D C Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095324 117 13095 Y84 Q P H E G S S Y S S R K D C Q
Dog Lupus familis XP_849319 191 21202 Y158 Q P H E G S S Y S S R K D C Q
Cat Felis silvestris
Mouse Mus musculus Q9D8C6 117 13112 Y84 Q P H E G S S Y S S R K D C Q
Rat Rattus norvegicus NP_001099269 135 15344 Y84 Q P H E G S S Y S S R K D C Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q68EW7 118 13196 Y84 Q P H E G S S Y S A R K D G T
Zebra Danio Brachydanio rerio A3KNK7 114 12768 Y79 Q P H E G S T Y S A R K D C Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVS4 176 19620 Y80 Q P H E G S G Y A S A K V L Q
Honey Bee Apis mellifera XP_625097 112 12757 E77 V S T G Q P H E G S G Y A S Q
Nematode Worm Caenorhab. elegans Q9BI74 188 20320 F88 S S H Q G S T F G V L Q N S L
Sea Urchin Strong. purpuratus XP_791981 85 9663 G52 S T G Q P H E G S S Y S A Q K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.1 61.2 N.A. 97.4 77.7 N.A. N.A. N.A. 76.2 65.8 N.A. 30.6 42.7 21.2 33.3
Protein Similarity: 100 N.A. 99.1 61.2 N.A. 98.2 80.7 N.A. N.A. N.A. 88.1 80.3 N.A. 46.5 65.8 37.7 52.9
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 80 86.6 N.A. 66.6 13.3 20 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 100 N.A. 73.3 13.3 53.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 10 19 10 0 19 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 55 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 % D
% Glu: 0 0 0 73 0 0 10 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 82 0 10 10 19 0 10 0 0 10 0 % G
% His: 0 0 82 0 0 10 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 73 0 0 10 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 73 0 0 10 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 73 0 0 19 10 0 0 0 0 0 0 10 0 10 73 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0 % R
% Ser: 19 19 0 0 0 82 55 0 73 73 0 10 0 19 0 % S
% Thr: 0 10 10 0 0 0 19 0 0 0 0 0 0 0 10 % T
% Val: 10 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 73 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _