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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM111
All Species:
32.12
Human Site:
S52
Identified Species:
58.89
UniProt:
Q9P0I2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0I2
NP_060917.1
261
29952
S52
T
Q
E
Q
V
S
D
S
Q
V
L
I
R
S
R
Chimpanzee
Pan troglodytes
XP_001150763
262
29870
S52
T
Q
E
Q
V
S
D
S
Q
V
L
I
R
S
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_861549
207
23442
L14
L
L
D
S
N
I
R
L
W
V
V
L
P
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99KI3
261
29961
S52
T
Q
E
Q
V
S
D
S
Q
V
L
I
R
S
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505672
261
30022
S52
T
Q
E
Q
V
S
D
S
Q
V
L
I
R
S
R
Chicken
Gallus gallus
XP_414280
261
30080
S52
T
Q
E
Q
V
S
D
S
Q
V
L
I
R
S
R
Frog
Xenopus laevis
NP_001087788
230
26270
L37
I
R
H
Y
V
S
I
L
L
Q
S
D
K
K
L
Zebra Danio
Brachydanio rerio
Q7SXW4
261
29773
S52
T
L
E
Q
V
S
D
S
Q
V
L
I
R
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609444
247
27648
S50
E
I
T
Q
I
Q
D
S
Q
A
M
I
R
A
R
Honey Bee
Apis mellifera
XP_623902
252
28570
S50
E
L
H
Q
V
Q
D
S
Q
V
M
I
R
S
R
Nematode Worm
Caenorhab. elegans
NP_502575
234
26523
K40
S
L
L
L
M
N
K
K
K
V
E
L
E
N
I
Sea Urchin
Strong. purpuratus
XP_782919
255
29349
S50
D
L
Q
K
V
G
D
S
Q
A
L
M
R
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36039
253
28333
I60
L
Q
W
A
Q
L
L
I
G
N
G
G
N
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
N.A.
76.2
N.A.
99.6
N.A.
N.A.
98
96.9
85
89.6
N.A.
58.6
66.2
48.2
65.9
Protein Similarity:
100
87.7
N.A.
77.3
N.A.
100
N.A.
N.A.
98.8
99.2
86.5
94.2
N.A.
73.5
80.4
69.3
83.1
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
N.A.
N.A.
100
100
13.3
93.3
N.A.
46.6
66.6
6.6
53.3
P-Site Similarity:
100
100
N.A.
26.6
N.A.
100
N.A.
N.A.
100
100
26.6
93.3
N.A.
66.6
73.3
46.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
16
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
70
0
0
0
0
8
0
0
0
% D
% Glu:
16
0
47
0
0
0
0
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
8
0
8
8
0
0
0
% G
% His:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
8
8
8
0
0
0
62
0
8
8
% I
% Lys:
0
0
0
8
0
0
8
8
8
0
0
0
8
8
0
% K
% Leu:
16
39
8
8
0
8
8
16
8
0
54
16
0
8
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
16
8
0
0
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
8
0
0
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
47
8
62
8
16
0
0
70
8
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
8
0
0
0
0
0
70
0
70
% R
% Ser:
8
0
0
8
0
54
0
70
0
0
8
0
0
62
8
% S
% Thr:
47
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
70
0
0
0
0
70
8
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _