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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM111
All Species:
29.7
Human Site:
S72
Identified Species:
54.44
UniProt:
Q9P0I2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0I2
NP_060917.1
261
29952
S72
G
K
Y
I
P
K
Q
S
F
L
T
R
K
Y
Y
Chimpanzee
Pan troglodytes
XP_001150763
262
29870
S72
G
K
Y
I
P
K
Q
S
F
L
T
R
K
Y
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_861549
207
23442
V34
V
G
M
I
R
H
Y
V
S
I
L
L
Q
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99KI3
261
29961
S72
G
K
Y
I
P
K
Q
S
F
L
T
R
K
Y
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505672
261
30022
S72
G
K
Y
I
P
K
Q
S
F
L
T
R
K
Y
F
Chicken
Gallus gallus
XP_414280
261
30080
S72
G
K
Y
I
P
K
Q
S
F
L
T
R
K
Y
Y
Frog
Xenopus laevis
NP_001087788
230
26270
R57
S
D
S
Q
V
L
I
R
S
R
V
L
R
E
N
Zebra Danio
Brachydanio rerio
Q7SXW4
261
29773
S72
G
K
Y
I
P
K
Q
S
F
L
M
R
K
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609444
247
27648
S70
G
K
Y
L
S
A
Q
S
F
S
M
R
K
N
Y
Honey Bee
Apis mellifera
XP_623902
252
28570
A70
G
Q
Y
I
P
K
M
A
F
I
S
R
R
H
F
Nematode Worm
Caenorhab. elegans
NP_502575
234
26523
R60
L
L
R
A
R
L
L
R
E
N
G
R
F
L
P
Sea Urchin
Strong. purpuratus
XP_782919
255
29349
S70
G
R
F
L
P
R
K
S
F
I
M
R
K
H
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36039
253
28333
K80
A
K
K
E
F
L
V
K
D
L
T
E
E
R
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
N.A.
76.2
N.A.
99.6
N.A.
N.A.
98
96.9
85
89.6
N.A.
58.6
66.2
48.2
65.9
Protein Similarity:
100
87.7
N.A.
77.3
N.A.
100
N.A.
N.A.
98.8
99.2
86.5
94.2
N.A.
73.5
80.4
69.3
83.1
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
N.A.
N.A.
93.3
100
0
86.6
N.A.
60
46.6
6.6
40
P-Site Similarity:
100
100
N.A.
20
N.A.
100
N.A.
N.A.
100
100
6.6
93.3
N.A.
66.6
93.3
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
0
0
0
0
8
0
0
8
8
8
0
% E
% Phe:
0
0
8
0
8
0
0
0
70
0
0
0
8
8
24
% F
% Gly:
70
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
16
8
% H
% Ile:
0
0
0
62
0
0
8
0
0
24
0
0
0
0
0
% I
% Lys:
0
62
8
0
0
54
8
8
0
0
0
0
62
0
0
% K
% Leu:
8
8
0
16
0
24
8
0
0
54
8
16
0
8
0
% L
% Met:
0
0
8
0
0
0
8
0
0
0
24
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% N
% Pro:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
8
0
8
0
0
54
0
0
0
0
0
8
0
0
% Q
% Arg:
0
8
8
0
16
8
0
16
0
8
0
77
16
8
0
% R
% Ser:
8
0
8
0
8
0
0
62
16
8
8
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
47
0
0
0
0
% T
% Val:
8
0
0
0
8
0
8
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
62
0
0
0
8
0
0
0
0
0
0
39
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _