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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM111
All Species:
28.18
Human Site:
T105
Identified Species:
51.67
UniProt:
Q9P0I2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0I2
NP_060917.1
261
29952
T105
P
S
P
M
T
D
P
T
M
L
T
D
M
M
K
Chimpanzee
Pan troglodytes
XP_001150763
262
29870
T105
P
S
P
M
T
D
P
T
M
L
T
D
M
M
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_861549
207
23442
Y67
V
L
R
E
N
G
K
Y
I
P
K
Q
S
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KI3
261
29961
T105
P
S
P
M
T
D
P
T
M
L
T
D
M
M
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505672
261
30022
T105
P
S
P
M
T
D
P
T
M
L
T
D
M
M
K
Chicken
Gallus gallus
XP_414280
261
30080
T105
P
S
P
M
T
D
P
T
M
L
T
D
M
M
K
Frog
Xenopus laevis
NP_001087788
230
26270
K90
S
E
D
G
F
F
K
K
T
K
R
K
V
V
P
Zebra Danio
Brachydanio rerio
Q7SXW4
261
29773
S105
P
S
P
M
T
D
P
S
M
L
T
D
M
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609444
247
27648
T103
Q
N
S
S
A
M
L
T
D
M
V
K
G
N
F
Honey Bee
Apis mellifera
XP_623902
252
28570
N103
Q
N
P
M
T
D
P
N
M
M
T
D
M
L
K
Nematode Worm
Caenorhab. elegans
NP_502575
234
26523
P93
L
S
K
A
Q
Q
R
P
A
K
G
P
N
P
M
Sea Urchin
Strong. purpuratus
XP_782919
255
29349
S103
Q
N
P
M
T
D
P
S
M
M
T
D
M
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36039
253
28333
N113
F
N
D
P
S
M
S
N
A
M
M
N
M
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
N.A.
76.2
N.A.
99.6
N.A.
N.A.
98
96.9
85
89.6
N.A.
58.6
66.2
48.2
65.9
Protein Similarity:
100
87.7
N.A.
77.3
N.A.
100
N.A.
N.A.
98.8
99.2
86.5
94.2
N.A.
73.5
80.4
69.3
83.1
P-Site Identity:
100
100
N.A.
0
N.A.
100
N.A.
N.A.
100
100
0
93.3
N.A.
6.6
66.6
6.6
66.6
P-Site Similarity:
100
100
N.A.
6.6
N.A.
100
N.A.
N.A.
100
100
13.3
100
N.A.
20
86.6
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
16
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
62
0
0
8
0
0
62
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
8
8
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
8
0
8
0
0
0
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
16
8
0
16
8
16
0
0
70
% K
% Leu:
8
8
0
0
0
0
8
0
0
47
0
0
0
16
8
% L
% Met:
0
0
0
62
0
16
0
0
62
31
8
0
70
47
8
% M
% Asn:
0
31
0
0
8
0
0
16
0
0
0
8
8
8
0
% N
% Pro:
47
0
62
8
0
0
62
8
0
8
0
8
0
8
8
% P
% Gln:
24
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% R
% Ser:
8
54
8
8
8
0
8
16
0
0
0
0
8
0
0
% S
% Thr:
0
0
0
0
62
0
0
47
8
0
62
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _