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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM111
All Species:
17.27
Human Site:
T220
Identified Species:
31.67
UniProt:
Q9P0I2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0I2
NP_060917.1
261
29952
T220
D
T
N
K
A
F
K
T
E
W
E
A
L
E
L
Chimpanzee
Pan troglodytes
XP_001150763
262
29870
V220
D
T
N
K
A
F
K
V
Y
S
F
T
F
Q
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_861549
207
23442
I182
N
V
F
G
L
R
S
I
Y
S
L
I
L
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99KI3
261
29961
T220
D
T
N
K
A
F
K
T
E
W
E
A
L
E
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505672
261
30022
T220
D
T
N
K
A
F
K
T
E
W
E
A
L
E
L
Chicken
Gallus gallus
XP_414280
261
30080
T220
D
T
N
K
A
F
K
T
E
W
E
A
L
E
L
Frog
Xenopus laevis
NP_001087788
230
26270
G205
V
M
Q
E
Q
M
T
G
A
A
M
A
M
P
A
Zebra Danio
Brachydanio rerio
Q7SXW4
261
29773
A220
D
T
N
K
A
F
K
A
E
W
E
A
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609444
247
27648
E218
A
A
F
K
A
E
W
E
A
L
E
I
T
E
Y
Honey Bee
Apis mellifera
XP_623902
252
28570
S218
D
P
K
A
A
F
K
S
E
W
E
A
L
E
I
Nematode Worm
Caenorhab. elegans
NP_502575
234
26523
V208
M
A
M
T
G
S
A
V
N
P
Q
A
D
P
R
Sea Urchin
Strong. purpuratus
XP_782919
255
29349
E218
P
T
K
A
F
K
G
E
W
E
A
L
E
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36039
253
28333
M228
V
D
K
A
M
H
A
M
A
N
D
L
T
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.8
N.A.
76.2
N.A.
99.6
N.A.
N.A.
98
96.9
85
89.6
N.A.
58.6
66.2
48.2
65.9
Protein Similarity:
100
87.7
N.A.
77.3
N.A.
100
N.A.
N.A.
98.8
99.2
86.5
94.2
N.A.
73.5
80.4
69.3
83.1
P-Site Identity:
100
46.6
N.A.
6.6
N.A.
100
N.A.
N.A.
100
100
6.6
93.3
N.A.
26.6
66.6
6.6
6.6
P-Site Similarity:
100
53.3
N.A.
13.3
N.A.
100
N.A.
N.A.
100
100
20
93.3
N.A.
26.6
80
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
24
62
0
16
8
24
8
8
62
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% D
% Glu:
0
0
0
8
0
8
0
16
47
8
54
0
8
54
0
% E
% Phe:
0
0
16
0
8
54
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
8
8
0
8
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
16
0
16
16
% I
% Lys:
0
0
24
54
0
8
54
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
0
8
8
16
54
0
39
% L
% Met:
8
8
8
0
8
8
0
8
0
0
8
0
8
0
0
% M
% Asn:
8
0
47
0
0
0
0
0
8
8
0
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
0
0
8
0
0
0
16
0
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
8
0
0
8
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
8
8
8
0
16
0
0
0
0
8
% S
% Thr:
0
54
0
8
0
0
8
31
0
0
0
8
16
0
0
% T
% Val:
16
8
0
0
0
0
0
16
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
47
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _