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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM22
All Species:
21.82
Human Site:
Y137
Identified Species:
53.33
UniProt:
Q9P0K1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0K1
NP_004185.1
906
100433
Y137
K
G
G
E
H
C
Y
Y
Q
G
H
I
R
G
N
Chimpanzee
Pan troglodytes
XP_001164271
906
100467
Y137
K
G
G
E
H
C
Y
Y
Q
G
H
I
R
G
N
Rhesus Macaque
Macaca mulatta
XP_001104527
899
100254
Y137
K
G
G
E
H
C
Y
Y
Q
G
H
I
R
G
N
Dog
Lupus familis
XP_859842
909
100488
Y140
K
G
G
E
H
C
Y
Y
Q
G
H
V
R
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1V6
904
99696
Y135
K
G
G
E
H
C
Y
Y
Q
G
Q
I
R
G
N
Rat
Rattus norvegicus
Q9QYV0
816
88034
Q63
I
N
L
T
E
V
L
Q
T
G
L
P
E
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518258
429
46933
Chicken
Gallus gallus
NP_001138700
825
92297
D72
P
D
E
N
Y
T
S
D
D
D
F
H
F
H
S
Frog
Xenopus laevis
O42596
935
104143
Y139
K
G
G
E
H
C
Y
Y
Q
G
Q
I
R
G
K
Zebra Danio
Brachydanio rerio
XP_695529
774
85179
A21
I
A
R
L
A
V
T
A
W
G
S
S
T
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
89.6
95.5
N.A.
91.5
29
N.A.
39.6
68.6
70.8
45.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
91.2
98
N.A.
95
44.1
N.A.
43.4
78.1
81.1
59.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
0
0
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
0
13.3
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
10
10
10
0
0
0
0
0
% D
% Glu:
0
0
10
60
10
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% F
% Gly:
0
60
60
0
0
0
0
0
0
80
0
0
0
60
0
% G
% His:
0
0
0
0
60
0
0
0
0
0
40
10
0
10
0
% H
% Ile:
20
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% I
% Lys:
60
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% K
% Leu:
0
0
10
10
0
0
10
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
50
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
60
0
20
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
60
0
10
% R
% Ser:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
10
% S
% Thr:
0
0
0
10
0
10
10
0
10
0
0
0
10
10
0
% T
% Val:
0
0
0
0
0
20
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
60
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _