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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADAM22 All Species: 19.39
Human Site: Y785 Identified Species: 47.41
UniProt: Q9P0K1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0K1 NP_004185.1 906 100433 Y785 P G D G D S F Y S D I P P G V
Chimpanzee Pan troglodytes XP_001164271 906 100467 Y785 P G D G D S F Y S D I P P G V
Rhesus Macaque Macaca mulatta XP_001104527 899 100254 I785 R I P D T K H I S D I C E N G
Dog Lupus familis XP_859842 909 100488 Y788 P G D G D S F Y S D I P P G V
Cat Felis silvestris
Mouse Mus musculus Q9R1V6 904 99696 Y783 P G D G D S F Y S D F P P G G
Rat Rattus norvegicus Q9QYV0 816 88034 S703 L T T G L L L S L L L L L V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518258 429 46933 D316 P Y N D G S K D D V F H P G N
Chicken Gallus gallus NP_001138700 825 92297 S712 S T N S A S S S K K R S N G L
Frog Xenopus laevis O42596 935 104143 Y785 P G D A D S F Y S D L P P G V
Zebra Danio Brachydanio rerio XP_695529 774 85179 G661 V E D G T P C G P N M M C L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 89.6 95.5 N.A. 91.5 29 N.A. 39.6 68.6 70.8 45.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 91.2 98 N.A. 95 44.1 N.A. 43.4 78.1 81.1 59.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 20 100 N.A. 86.6 6.6 N.A. 26.6 13.3 86.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 86.6 20 N.A. 33.3 26.6 93.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 10 10 0 0 % C
% Asp: 0 0 60 20 50 0 0 10 10 60 0 0 0 0 10 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 50 0 0 0 20 0 0 0 0 % F
% Gly: 0 50 0 60 10 0 0 10 0 0 0 0 0 70 20 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 10 0 0 40 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 10 0 10 10 0 0 0 0 0 % K
% Leu: 10 0 0 0 10 10 10 0 10 10 20 10 10 10 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % M
% Asn: 0 0 20 0 0 0 0 0 0 10 0 0 10 10 10 % N
% Pro: 60 0 10 0 0 10 0 0 10 0 0 50 60 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 10 0 0 10 0 70 10 20 60 0 0 10 0 0 0 % S
% Thr: 0 20 10 0 20 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 10 0 0 0 10 40 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _