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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAPA All Species: 27.58
Human Site: S164 Identified Species: 55.15
UniProt: Q9P0L0 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0L0 NP_003565.4 249 27893 S164 G P M P K P H S V S L N D T E
Chimpanzee Pan troglodytes XP_001135371 233 26380 E155 S V S L N D T E T R K L M E E
Rhesus Macaque Macaca mulatta XP_001118496 276 30934 S191 G P M P K P H S V S L N D T E
Dog Lupus familis XP_859767 249 27827 S164 G P M P K P H S V S L N D T E
Cat Felis silvestris
Mouse Mus musculus Q9WV55 249 27837 S164 G P L P K P H S V S L N D T E
Rat Rattus norvegicus Q9Z270 249 27823 S164 G P L P K P H S V S L N D T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512295 393 42526 S308 G P V P K P H S A S L S D T E
Chicken Gallus gallus NP_001006296 243 27255 R175 K V M E E Y K R L Q V E V Q R
Frog Xenopus laevis NP_001088528 243 27333 S158 S S L S K S I S S N L D D S E
Zebra Danio Brachydanio rerio NP_001002546 246 27491 S159 L L S V K P L S G A H D D S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785910 241 26909 L161 P Q V G E E K L E T R D L D T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40075 244 26907 K165 V P A V V N E K E V P A E P E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 81.1 98.3 N.A. 97.1 96.7 N.A. 58.2 62.6 57.4 71.4 N.A. N.A. N.A. N.A. 45.3
Protein Similarity: 100 91.5 81.8 98.8 N.A. 98.3 98.3 N.A. 61.8 75 73.4 84.7 N.A. N.A. N.A. N.A. 63.8
P-Site Identity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 80 6.6 33.3 33.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 93.3 26.6 60 53.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 9 9 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 0 25 67 9 0 % D
% Glu: 0 0 0 9 17 9 9 9 17 0 0 9 9 9 84 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 50 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 67 0 17 9 0 0 9 0 0 0 0 % K
% Leu: 9 9 25 9 0 0 9 9 9 0 59 9 9 0 0 % L
% Met: 0 0 34 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 9 0 42 0 0 0 % N
% Pro: 9 59 0 50 0 59 0 0 0 0 9 0 0 9 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 9 0 0 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 9 0 9 9 0 0 0 9 % R
% Ser: 17 9 17 9 0 9 0 67 9 50 0 9 0 17 0 % S
% Thr: 0 0 0 0 0 0 9 0 9 9 0 0 0 50 9 % T
% Val: 9 17 17 17 9 0 0 0 42 9 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _