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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VAPA
All Species:
23.64
Human Site:
S166
Identified Species:
47.27
UniProt:
Q9P0L0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0L0
NP_003565.4
249
27893
S166
M
P
K
P
H
S
V
S
L
N
D
T
E
T
R
Chimpanzee
Pan troglodytes
XP_001135371
233
26380
R157
S
L
N
D
T
E
T
R
K
L
M
E
E
C
K
Rhesus Macaque
Macaca mulatta
XP_001118496
276
30934
S193
M
P
K
P
H
S
V
S
L
N
D
T
E
T
R
Dog
Lupus familis
XP_859767
249
27827
S166
M
P
K
P
H
S
V
S
L
N
D
T
E
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV55
249
27837
S166
L
P
K
P
H
S
V
S
L
N
D
T
E
T
R
Rat
Rattus norvegicus
Q9Z270
249
27823
S166
L
P
K
P
H
S
V
S
L
N
D
T
E
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512295
393
42526
S310
V
P
K
P
H
S
A
S
L
S
D
T
E
T
K
Chicken
Gallus gallus
NP_001006296
243
27255
Q177
M
E
E
Y
K
R
L
Q
V
E
V
Q
R
L
R
Frog
Xenopus laevis
NP_001088528
243
27333
N160
L
S
K
S
I
S
S
N
L
D
D
S
E
Y
K
Zebra Danio
Brachydanio rerio
NP_001002546
246
27491
A161
S
V
K
P
L
S
G
A
H
D
D
S
E
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785910
241
26909
T163
V
G
E
E
K
L
E
T
R
D
L
D
T
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40075
244
26907
V167
A
V
V
N
E
K
E
V
P
A
E
P
E
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
81.1
98.3
N.A.
97.1
96.7
N.A.
58.2
62.6
57.4
71.4
N.A.
N.A.
N.A.
N.A.
45.3
Protein Similarity:
100
91.5
81.8
98.8
N.A.
98.3
98.3
N.A.
61.8
75
73.4
84.7
N.A.
N.A.
N.A.
N.A.
63.8
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
73.3
13.3
33.3
40
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
93.3
33.3
66.6
60
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
9
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
25
67
9
0
0
0
% D
% Glu:
0
9
17
9
9
9
17
0
0
9
9
9
84
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
50
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
67
0
17
9
0
0
9
0
0
0
0
0
25
% K
% Leu:
25
9
0
0
9
9
9
0
59
9
9
0
0
9
0
% L
% Met:
34
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% M
% Asn:
0
0
9
9
0
0
0
9
0
42
0
0
0
0
0
% N
% Pro:
0
50
0
59
0
0
0
0
9
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
9
0
9
9
0
0
0
9
0
59
% R
% Ser:
17
9
0
9
0
67
9
50
0
9
0
17
0
0
0
% S
% Thr:
0
0
0
0
9
0
9
9
0
0
0
50
9
59
0
% T
% Val:
17
17
9
0
0
0
42
9
9
0
9
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _