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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAPA All Species: 28.18
Human Site: S216 Identified Species: 56.36
UniProt: Q9P0L0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0L0 NP_003565.4 249 27893 S216 S D K P G S T S T A S F R D N
Chimpanzee Pan troglodytes XP_001135371 233 26380 S200 S D K P G S T S T A S F R D N
Rhesus Macaque Macaca mulatta XP_001118496 276 30934 S243 S D K P G S T S T A S F R D N
Dog Lupus familis XP_859767 249 27827 S216 S D K P G S T S A A S F R D N
Cat Felis silvestris
Mouse Mus musculus Q9WV55 249 27837 S216 S D K P G S T S A V S F R D N
Rat Rattus norvegicus Q9Z270 249 27823 S216 S D K P G S T S A V S F R D N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512295 393 42526 S360 S D K P G S S S S M I P R E N
Chicken Gallus gallus NP_001006296 243 27255 S221 V V K D E G H S S R L L A L V
Frog Xenopus laevis NP_001088528 243 27333 V211 T S S P H R P V S G L A K E E
Zebra Danio Brachydanio rerio NP_001002546 246 27491 S213 D H V S S N S S T S V G R D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785910 241 26909 V209 G G Q P M K T V S P T V T E T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40075 244 26907 A215 Q N Q I K E A A T V P A E N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 81.1 98.3 N.A. 97.1 96.7 N.A. 58.2 62.6 57.4 71.4 N.A. N.A. N.A. N.A. 45.3
Protein Similarity: 100 91.5 81.8 98.8 N.A. 98.3 98.3 N.A. 61.8 75 73.4 84.7 N.A. N.A. N.A. N.A. 63.8
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 60 13.3 6.6 26.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 80 20 33.3 53.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 9 25 34 0 17 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 59 0 9 0 0 0 0 0 0 0 0 0 59 0 % D
% Glu: 0 0 0 0 9 9 0 0 0 0 0 0 9 25 17 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % F
% Gly: 9 9 0 0 59 9 0 0 0 9 0 9 0 0 0 % G
% His: 0 9 0 0 9 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 67 0 9 9 0 0 0 0 0 0 9 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 17 9 0 9 0 % L
% Met: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 9 0 0 0 0 0 0 0 9 59 % N
% Pro: 0 0 0 75 0 0 9 0 0 9 9 9 0 0 0 % P
% Gln: 9 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 9 0 0 67 0 0 % R
% Ser: 59 9 9 9 9 59 17 75 34 9 50 0 0 0 9 % S
% Thr: 9 0 0 0 0 0 59 0 42 0 9 0 9 0 9 % T
% Val: 9 9 9 0 0 0 0 17 0 25 9 9 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _