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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VAPA All Species: 29.09
Human Site: T170 Identified Species: 58.18
UniProt: Q9P0L0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0L0 NP_003565.4 249 27893 T170 H S V S L N D T E T R K L M E
Chimpanzee Pan troglodytes XP_001135371 233 26380 E161 T E T R K L M E E C K R L Q G
Rhesus Macaque Macaca mulatta XP_001118496 276 30934 T197 H S V S L N D T E T R K L M E
Dog Lupus familis XP_859767 249 27827 T170 H S V S L N D T E T R K L M E
Cat Felis silvestris
Mouse Mus musculus Q9WV55 249 27837 T170 H S V S L N D T E T R K L M E
Rat Rattus norvegicus Q9Z270 249 27823 T170 H S V S L N D T E T R K L M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512295 393 42526 T314 H S A S L S D T E T K K L M E
Chicken Gallus gallus NP_001006296 243 27255 Q181 K R L Q V E V Q R L R E E N K
Frog Xenopus laevis NP_001088528 243 27333 S164 I S S N L D D S E Y K K V A E
Zebra Danio Brachydanio rerio NP_001002546 246 27491 S165 L S G A H D D S E M R R I L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785910 241 26909 D167 K L E T R D L D T V V K E C K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40075 244 26907 P171 E K E V P A E P E T Q P P V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 81.1 98.3 N.A. 97.1 96.7 N.A. 58.2 62.6 57.4 71.4 N.A. N.A. N.A. N.A. 45.3
Protein Similarity: 100 91.5 81.8 98.8 N.A. 98.3 98.3 N.A. 61.8 75 73.4 84.7 N.A. N.A. N.A. N.A. 63.8
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 80 6.6 40 33.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 93.3 33.3 73.3 73.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 9 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 25 67 9 0 0 0 0 0 0 0 % D
% Glu: 9 9 17 0 0 9 9 9 84 0 0 9 17 0 67 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % G
% His: 50 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 17 9 0 0 9 0 0 0 0 0 25 67 0 0 17 % K
% Leu: 9 9 9 0 59 9 9 0 0 9 0 0 59 9 0 % L
% Met: 0 0 0 0 0 0 9 0 0 9 0 0 0 50 0 % M
% Asn: 0 0 0 9 0 42 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 9 0 0 9 0 0 0 9 9 0 0 % P
% Gln: 0 0 0 9 0 0 0 9 0 0 9 0 0 9 9 % Q
% Arg: 0 9 0 9 9 0 0 0 9 0 59 17 0 0 0 % R
% Ser: 0 67 9 50 0 9 0 17 0 0 0 0 0 0 0 % S
% Thr: 9 0 9 9 0 0 0 50 9 59 0 0 0 0 0 % T
% Val: 0 0 42 9 9 0 9 0 0 9 9 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _