KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK1
All Species:
8.18
Human Site:
Y177
Identified Species:
15
UniProt:
Q9P0L2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0L2
NP_061120.3
795
89003
Y177
V
Q
Y
C
H
Q
K
Y
I
V
H
R
D
L
K
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
Y177
V
Q
Y
C
H
Q
K
Y
I
V
H
R
D
L
K
Rhesus Macaque
Macaca mulatta
XP_001115611
778
86745
F170
V
Q
Y
C
H
Q
K
F
I
V
H
R
D
L
K
Dog
Lupus familis
XP_536123
782
87409
C164
V
Q
Y
C
H
Q
K
C
I
V
H
R
D
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHJ5
795
88528
C177
V
Q
Y
C
H
Q
K
C
I
V
H
R
D
L
K
Rat
Rattus norvegicus
O08678
793
88216
C177
V
Q
Y
C
H
Q
K
C
I
V
H
R
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
C176
V
Q
Y
C
H
Q
K
C
I
V
H
R
D
L
K
Chicken
Gallus gallus
Q9IA88
798
88848
L156
L
K
T
E
N
L
L
L
D
A
N
M
N
I
K
Frog
Xenopus laevis
NP_001085126
792
88624
C177
V
Q
Y
C
H
Q
K
C
I
V
H
R
D
L
K
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S176
V
Y
F
C
H
C
R
S
I
V
H
R
D
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
N287
V
Q
Y
L
H
S
K
N
I
I
H
R
D
L
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
I57
A
H
I
G
N
Y
Q
I
V
K
T
L
G
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
68.9
95.9
N.A.
94.9
94.3
N.A.
92.8
30.4
88.6
27.8
N.A.
N.A.
N.A.
40.7
N.A.
Protein Similarity:
100
99.3
80.2
96.8
N.A.
97.3
96.9
N.A.
95.9
51.3
94.2
44
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
6.6
93.3
66.6
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
46.6
93.3
80
N.A.
N.A.
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.4
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
70
0
8
0
39
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
77
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
8
0
0
77
0
0
0
0
0
77
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
77
8
0
0
0
8
0
% I
% Lys:
0
8
0
0
0
0
70
0
0
8
0
0
0
0
85
% K
% Leu:
8
0
0
8
0
8
8
8
0
0
0
8
0
77
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
8
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
70
0
0
0
62
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
77
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
77
0
0
0
0
0
0
0
8
70
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
70
0
0
8
0
16
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _