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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK1
All Species:
20.3
Human Site:
Y24
Identified Species:
37.22
UniProt:
Q9P0L2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0L2
NP_061120.3
795
89003
Y24
N
H
T
S
V
D
G
Y
T
E
P
H
I
Q
P
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
Y24
N
H
T
S
V
D
G
Y
T
E
P
L
I
Q
P
Rhesus Macaque
Macaca mulatta
XP_001115611
778
86745
D25
Q
P
T
L
G
H
L
D
S
K
P
S
S
K
S
Dog
Lupus familis
XP_536123
782
87409
Q25
P
T
K
S
S
S
R
Q
N
I
P
R
C
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHJ5
795
88528
Y24
N
H
T
S
V
D
G
Y
T
E
T
H
I
P
P
Rat
Rattus norvegicus
O08678
793
88216
Y24
N
H
T
S
V
D
G
Y
T
E
T
H
I
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
Y24
N
H
T
S
V
D
G
Y
T
E
P
H
I
Q
P
Chicken
Gallus gallus
Q9IA88
798
88848
G24
Q
P
R
P
L
R
V
G
F
Y
D
I
E
R
T
Frog
Xenopus laevis
NP_001085126
792
88624
Y24
N
H
T
S
L
D
G
Y
P
E
P
P
V
P
P
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P24
P
N
P
N
R
E
R
P
Q
Q
Q
Q
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
H134
Y
S
S
S
G
R
S
H
P
T
S
G
S
S
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
68.9
95.9
N.A.
94.9
94.3
N.A.
92.8
30.4
88.6
27.8
N.A.
N.A.
N.A.
40.7
N.A.
Protein Similarity:
100
99.3
80.2
96.8
N.A.
97.3
96.9
N.A.
95.9
51.3
94.2
44
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
93.3
13.3
13.3
N.A.
86.6
86.6
N.A.
100
0
66.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
93.3
33.3
20
N.A.
86.6
86.6
N.A.
100
13.3
80
33.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.4
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
0
47
0
8
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
47
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
16
0
47
8
0
0
0
8
0
0
0
% G
% His:
0
47
0
0
0
8
0
8
0
0
0
31
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
8
39
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
8
16
0
8
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
8
0
8
0
0
0
0
8
0
0
0
0
0
8
% N
% Pro:
16
16
8
8
0
0
0
8
16
0
47
8
0
24
47
% P
% Gln:
16
0
0
0
0
0
0
8
8
8
8
8
8
31
8
% Q
% Arg:
0
0
8
0
8
16
16
0
0
0
0
8
0
16
0
% R
% Ser:
0
8
8
62
8
8
8
0
8
0
8
8
16
8
16
% S
% Thr:
0
8
54
0
0
0
0
0
39
8
16
0
0
0
8
% T
% Val:
0
0
0
0
39
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
47
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _