KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK1
All Species:
24.85
Human Site:
Y627
Identified Species:
45.56
UniProt:
Q9P0L2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0L2
NP_061120.3
795
89003
Y627
R
E
R
R
S
V
A
Y
N
G
P
P
A
S
P
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
Y628
R
E
R
R
S
A
A
Y
N
G
P
P
A
S
P
Rhesus Macaque
Macaca mulatta
XP_001115611
778
86745
Y612
R
D
Q
Q
N
L
P
Y
G
V
T
P
A
S
P
Dog
Lupus familis
XP_536123
782
87409
Y614
R
E
R
R
S
A
A
Y
N
G
P
P
A
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHJ5
795
88528
Y627
R
E
R
R
S
A
A
Y
N
G
R
P
A
S
P
Rat
Rattus norvegicus
O08678
793
88216
Y627
R
E
R
R
S
A
A
Y
S
G
P
P
A
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
Y625
R
E
R
R
N
A
T
Y
N
G
P
P
A
S
P
Chicken
Gallus gallus
Q9IA88
798
88848
G601
A
R
A
K
G
F
L
G
L
N
K
I
K
G
F
Frog
Xenopus laevis
NP_001085126
792
88624
P627
R
T
A
T
Y
N
G
P
P
A
S
P
A
H
E
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P755
Y
Q
S
P
S
D
S
P
P
P
T
S
L
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
I1024
A
N
N
A
E
A
T
I
W
S
K
L
S
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
S355
Q
E
T
T
D
S
G
S
N
P
M
R
T
P
E
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
Q476
I
L
P
T
S
L
P
Q
I
H
R
A
N
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
68.9
95.9
N.A.
94.9
94.3
N.A.
92.8
30.4
88.6
27.8
N.A.
N.A.
N.A.
40.7
N.A.
Protein Similarity:
100
99.3
80.2
96.8
N.A.
97.3
96.9
N.A.
95.9
51.3
94.2
44
N.A.
N.A.
N.A.
51
N.A.
P-Site Identity:
100
93.3
40
93.3
N.A.
86.6
86.6
N.A.
80
0
20
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
93.3
73.3
93.3
N.A.
86.6
93.3
N.A.
86.6
6.6
20
20
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.9
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.4
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
8
0
47
39
0
0
8
0
8
62
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
54
0
0
8
0
0
0
0
0
0
0
0
0
16
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
0
16
8
8
47
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
16
0
8
8
0
% K
% Leu:
0
8
0
0
0
16
8
0
8
0
0
8
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
8
8
0
16
8
0
0
47
8
0
0
8
0
0
% N
% Pro:
0
0
8
8
0
0
16
16
16
16
39
62
0
16
54
% P
% Gln:
8
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
62
8
47
47
0
0
0
0
0
0
16
8
0
0
8
% R
% Ser:
0
0
8
0
54
8
8
8
8
8
8
8
8
54
0
% S
% Thr:
0
8
8
24
0
0
16
0
0
0
16
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _