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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKD2L1
All Species:
9.39
Human Site:
Y189
Identified Species:
25.83
UniProt:
Q9P0L9
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0L9
NP_057196.2
805
91982
Y189
H
G
S
H
S
F
I
Y
Y
E
N
M
L
L
G
Chimpanzee
Pan troglodytes
XP_001168415
805
91946
Y189
H
G
S
H
S
F
I
Y
Y
E
N
M
L
L
G
Rhesus Macaque
Macaca mulatta
XP_001107776
782
88861
L187
S
F
I
Y
Y
E
N
L
L
L
G
V
P
R
L
Dog
Lupus familis
XP_543967
1184
133713
Y510
H
G
S
H
S
F
I
Y
Y
E
N
L
L
L
G
Cat
Felis silvestris
Mouse
Mus musculus
O35245
966
108978
I307
Q
A
D
N
R
S
F
I
F
Y
E
N
L
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509851
916
103775
S237
L
P
G
H
K
N
N
S
R
I
Y
Y
E
N
L
Chicken
Gallus gallus
XP_426509
889
101491
I223
A
H
N
T
Q
S
Y
I
Y
Y
E
N
L
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1S7
716
80416
N154
E
T
S
N
S
T
D
N
E
N
M
I
Y
Y
E
Sea Urchin
Strong. purpuratus
NP_999827
907
103454
I245
T
D
D
E
L
G
Y
I
F
Y
E
N
K
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
91.5
61.6
N.A.
42.4
N.A.
N.A.
39.2
64.3
N.A.
N.A.
N.A.
N.A.
N.A.
34.1
43.5
Protein Similarity:
100
99.6
93.7
64.6
N.A.
58.4
N.A.
N.A.
56.9
75
N.A.
N.A.
N.A.
N.A.
N.A.
53
59.7
P-Site Identity:
100
100
0
93.3
N.A.
13.3
N.A.
N.A.
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
26.6
N.A.
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
23
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
12
0
12
0
0
12
34
34
0
12
0
12
% E
% Phe:
0
12
0
0
0
34
12
0
23
0
0
0
0
0
0
% F
% Gly:
0
34
12
0
0
12
0
0
0
0
12
0
0
0
34
% G
% His:
34
12
0
45
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
34
34
0
12
0
12
0
0
0
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
0
0
0
12
0
0
12
12
12
0
12
56
67
56
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
23
0
0
0
% M
% Asn:
0
0
12
23
0
12
23
12
0
12
34
34
0
12
0
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
0
12
0
0
0
0
12
0
% R
% Ser:
12
0
45
0
45
23
0
12
0
0
0
0
0
0
0
% S
% Thr:
12
12
0
12
0
12
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
12
0
23
34
45
34
12
12
12
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _