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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H2AFY2
All Species:
22.73
Human Site:
S251
Identified Species:
41.67
UniProt:
Q9P0M6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0M6
NP_061119.1
372
40058
S251
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
Chimpanzee
Pan troglodytes
XP_001170515
372
39969
S251
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
Rhesus Macaque
Macaca mulatta
XP_001109286
372
40070
S251
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
Dog
Lupus familis
XP_861204
372
40010
S251
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCK0
372
40074
S251
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
Rat
Rattus norvegicus
Q02874
371
39485
K250
A
V
L
E
L
R
K
K
N
G
P
L
E
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508461
342
36516
S221
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
Chicken
Gallus gallus
O93327
372
39638
K251
A
V
I
E
L
R
K
K
N
G
P
L
D
I
A
Frog
Xenopus laevis
P06897
130
13948
A13
K
Q
G
G
K
T
R
A
K
A
K
T
R
S
S
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
F26
S
S
R
A
G
L
Q
F
P
V
G
R
V
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P09588
127
13386
K11
R
G
K
G
G
K
A
K
T
G
G
K
A
K
S
Sea Urchin
Strong. purpuratus
P16886
126
13432
K10
G
R
G
K
G
A
G
K
A
R
A
K
A
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X132
134
14136
Q18
A
S
G
S
K
N
A
Q
S
R
S
S
K
A
G
Conservation
Percent
Protein Identity:
100
98.3
99.7
99.1
N.A.
98.3
68
N.A.
85.4
67.7
24.7
25
N.A.
N.A.
N.A.
23.9
24.4
Protein Similarity:
100
98.3
99.7
99.1
N.A.
98.9
79.8
N.A.
88.4
80.3
29.2
31.4
N.A.
N.A.
N.A.
28.4
28.7
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
100
60
0
0
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
100
73.3
26.6
20
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
25.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
0
8
0
8
16
8
8
8
8
0
16
8
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
62
0
0
0
0
0
0
0
0
54
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
8
24
16
24
0
8
0
0
70
16
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
54
8
16
8
62
31
8
0
8
16
8
16
0
% K
% Leu:
0
0
8
0
62
8
0
0
0
0
0
62
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
16
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
62
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
8
47
0
0
0
0
0
0
% Q
% Arg:
8
8
8
0
0
62
8
0
0
16
0
8
8
0
8
% R
% Ser:
8
16
0
8
0
0
0
47
8
0
8
8
0
8
24
% S
% Thr:
47
0
0
0
0
8
0
0
8
0
0
8
0
0
0
% T
% Val:
0
62
0
0
0
0
0
0
0
8
0
0
8
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _