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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D7
All Species:
18.18
Human Site:
S124
Identified Species:
33.33
UniProt:
Q9P0N9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0N9
NP_001137436.1
293
33972
S124
G
K
L
P
R
S
P
S
F
P
L
E
P
D
D
Chimpanzee
Pan troglodytes
XP_518243
293
33935
S124
G
K
L
P
R
S
P
S
F
P
L
E
P
E
D
Rhesus Macaque
Macaca mulatta
XP_001110360
173
20351
Y14
R
N
F
R
S
V
Y
Y
E
K
V
G
F
R
G
Dog
Lupus familis
XP_535890
293
33989
S124
G
K
L
P
R
S
P
S
F
P
L
E
P
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0K0
293
33808
S124
G
K
L
P
R
S
P
S
F
P
L
E
P
E
D
Rat
Rattus norvegicus
NP_001101881
293
33820
S124
G
K
L
P
R
S
P
S
F
P
L
E
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514908
293
34092
N124
G
K
L
P
R
N
P
N
F
P
L
E
Q
E
D
Chicken
Gallus gallus
XP_418942
270
31336
F111
Q
E
P
E
D
E
V
F
L
A
I
A
K
A
M
Frog
Xenopus laevis
NP_001084522
293
34178
P124
G
K
L
S
Q
C
Q
P
Y
P
M
E
P
E
D
Zebra Danio
Brachydanio rerio
NP_957071
294
33970
E124
H
T
L
P
R
R
T
E
L
R
P
P
D
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651223
306
36069
W123
A
Q
V
M
H
T
M
W
L
I
E
S
N
R
L
Honey Bee
Apis mellifera
XP_001121408
265
31268
F106
Y
T
K
P
H
L
M
F
L
T
I
A
M
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201202
171
20067
E12
N
F
R
S
H
Y
Y
E
K
V
G
F
R
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
57
93.1
N.A.
90.7
91.4
N.A.
86.3
73.3
73.3
65.6
N.A.
31.3
37.5
N.A.
31.4
Protein Similarity:
100
100
58.3
96.2
N.A.
95.9
94.8
N.A.
94.5
83.2
86
79.2
N.A.
50.9
55.2
N.A.
44.7
P-Site Identity:
100
93.3
0
93.3
N.A.
93.3
86.6
N.A.
73.3
0
46.6
20
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
100
6.6
100
N.A.
100
93.3
N.A.
93.3
13.3
73.3
26.6
N.A.
20
13.3
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
8
0
16
0
16
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
54
% D
% Glu:
0
8
0
8
0
8
0
16
8
0
8
54
0
47
8
% E
% Phe:
0
8
8
0
0
0
0
16
47
0
0
8
8
0
0
% F
% Gly:
54
0
0
0
0
0
0
0
0
0
8
8
0
8
8
% G
% His:
8
0
0
0
24
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
16
0
0
0
0
% I
% Lys:
0
54
8
0
0
0
0
0
8
8
0
0
8
0
0
% K
% Leu:
0
0
62
0
0
8
0
0
31
0
47
0
8
0
8
% L
% Met:
0
0
0
8
0
0
16
0
0
0
8
0
8
0
8
% M
% Asn:
8
8
0
0
0
8
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
8
62
0
0
47
8
0
54
8
8
39
0
0
% P
% Gln:
8
8
0
0
8
0
8
0
0
0
0
0
8
0
0
% Q
% Arg:
8
0
8
8
54
8
0
0
0
8
0
0
8
16
8
% R
% Ser:
0
0
0
16
8
39
0
39
0
0
0
8
0
8
0
% S
% Thr:
0
16
0
0
0
8
8
0
0
8
0
0
0
0
0
% T
% Val:
0
0
8
0
0
8
8
0
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
16
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _