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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D7
All Species:
35.45
Human Site:
S218
Identified Species:
65
UniProt:
Q9P0N9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0N9
NP_001137436.1
293
33972
S218
F
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
Chimpanzee
Pan troglodytes
XP_518243
293
33935
S218
F
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
Rhesus Macaque
Macaca mulatta
XP_001110360
173
20351
S99
L
K
V
V
R
F
V
S
D
A
T
P
Q
A
E
Dog
Lupus familis
XP_535890
293
33989
S218
F
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0K0
293
33808
S218
F
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
Rat
Rattus norvegicus
NP_001101881
293
33820
S218
F
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514908
293
34092
T218
F
A
G
C
L
P
E
T
S
L
Q
R
I
W
D
Chicken
Gallus gallus
XP_418942
270
31336
S196
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
K
Frog
Xenopus laevis
NP_001084522
293
34178
S218
F
A
G
C
L
S
A
S
S
L
Q
R
A
W
D
Zebra Danio
Brachydanio rerio
NP_957071
294
33970
S219
F
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651223
306
36069
T231
F
A
G
I
I
C
T
T
H
L
V
K
I
W
D
Honey Bee
Apis mellifera
XP_001121408
265
31268
S191
P
Y
D
I
W
F
S
S
C
F
A
G
T
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001201202
171
20067
D97
K
V
M
S
A
I
N
D
E
T
P
M
S
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
57
93.1
N.A.
90.7
91.4
N.A.
86.3
73.3
73.3
65.6
N.A.
31.3
37.5
N.A.
31.4
Protein Similarity:
100
100
58.3
96.2
N.A.
95.9
94.8
N.A.
94.5
83.2
86
79.2
N.A.
50.9
55.2
N.A.
44.7
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
86.6
6.6
80
100
N.A.
40
6.6
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
13.3
80
100
N.A.
66.6
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
70
0
0
8
0
8
0
0
8
8
0
8
8
0
% A
% Cys:
0
0
8
62
0
8
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
0
8
0
0
0
0
8
8
0
0
0
0
8
70
% D
% Glu:
0
0
0
0
0
8
54
0
8
0
0
0
0
0
8
% E
% Phe:
70
0
0
0
0
16
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
8
70
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
8
8
0
0
0
0
0
0
16
8
0
% I
% Lys:
8
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% K
% Leu:
8
0
0
8
62
0
0
0
8
70
0
0
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
8
54
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
62
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
8
62
0
0
0
% R
% Ser:
0
0
0
8
0
8
16
77
62
0
0
0
8
0
8
% S
% Thr:
0
0
0
0
0
0
8
16
0
8
8
0
8
0
0
% T
% Val:
0
8
8
8
0
0
8
0
0
0
8
8
47
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
8
70
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _