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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF181
All Species:
17.58
Human Site:
S70
Identified Species:
38.67
UniProt:
Q9P0P0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0P0
NP_057578.1
153
17909
S70
P
R
T
V
I
R
G
S
Q
A
E
L
K
C
P
Chimpanzee
Pan troglodytes
XP_515588
153
17865
S70
P
R
T
V
I
R
G
S
Q
A
E
L
K
C
P
Rhesus Macaque
Macaca mulatta
XP_001087546
153
17878
S70
P
R
T
V
I
R
G
S
Q
A
E
L
K
C
P
Dog
Lupus familis
XP_532978
153
17840
S70
P
R
T
V
I
R
S
S
Q
A
E
L
K
C
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY62
165
19082
A82
P
R
T
V
I
S
S
A
K
A
D
L
K
C
P
Rat
Rattus norvegicus
Q6AXU4
165
19269
S82
P
R
T
V
I
R
S
S
K
A
E
L
K
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513994
156
17964
A71
P
T
A
V
I
T
E
A
Q
A
D
K
G
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GPV5
156
17823
E71
P
K
V
T
V
T
P
E
Q
A
D
A
A
L
K
Zebra Danio
Brachydanio rerio
Q7ZW78
156
18015
E71
P
V
V
I
I
S
P
E
Q
A
D
K
G
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VE61
147
17019
D63
V
H
E
I
V
K
S
D
E
G
G
D
L
E
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150472
298
31648
E218
Q
V
V
A
V
R
G
E
E
V
V
Q
E
C
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
92.8
N.A.
79.3
81.8
N.A.
69.2
N.A.
67.3
64
N.A.
37.2
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.3
95.4
N.A.
87.2
88.4
N.A.
82
N.A.
80.1
79.4
N.A.
55.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
66.6
86.6
N.A.
33.3
N.A.
20
26.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
46.6
N.A.
40
40
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
32.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
19
0
82
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
10
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
37
10
0
0
0
% D
% Glu:
0
0
10
0
0
0
10
28
19
0
46
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
37
0
0
10
10
0
19
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
73
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
10
0
0
19
0
0
19
55
0
28
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
55
10
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
82
0
0
0
0
0
19
0
0
0
0
0
0
0
55
% P
% Gln:
10
0
0
0
0
0
0
0
64
0
0
10
0
0
0
% Q
% Arg:
0
55
0
0
0
55
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
19
37
46
0
0
0
0
0
0
0
% S
% Thr:
0
10
55
10
0
19
0
0
0
0
0
0
0
0
0
% T
% Val:
10
19
28
64
28
0
0
0
0
10
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _