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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF181
All Species:
20.3
Human Site:
T19
Identified Species:
44.67
UniProt:
Q9P0P0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0P0
NP_057578.1
153
17909
T19
P
S
D
P
E
Q
E
T
R
T
N
M
L
L
E
Chimpanzee
Pan troglodytes
XP_515588
153
17865
T19
P
S
D
P
E
Q
E
T
R
T
N
M
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001087546
153
17878
T19
P
S
D
P
E
Q
E
T
R
T
N
M
L
L
E
Dog
Lupus familis
XP_532978
153
17840
A19
P
L
D
S
E
Q
E
A
R
T
S
M
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY62
165
19082
A19
P
L
N
P
E
R
E
A
R
N
N
M
L
L
E
Rat
Rattus norvegicus
Q6AXU4
165
19269
A19
P
L
N
P
E
R
E
A
R
N
N
M
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513994
156
17964
Y19
P
G
L
P
E
E
Q
Y
R
Q
N
A
L
L
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GPV5
156
17823
Y19
P
T
V
P
E
E
Q
Y
R
Q
N
A
L
L
E
Zebra Danio
Brachydanio rerio
Q7ZW78
156
18015
Y19
P
T
N
P
E
E
Q
Y
R
Q
N
A
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VE61
147
17019
N19
P
T
G
P
L
G
A
N
D
L
A
R
N
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150472
298
31648
S142
G
V
M
E
G
I
D
S
G
D
D
D
S
I
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
92.8
N.A.
79.3
81.8
N.A.
69.2
N.A.
67.3
64
N.A.
37.2
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.3
95.4
N.A.
87.2
88.4
N.A.
82
N.A.
80.1
79.4
N.A.
55.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
66.6
N.A.
53.3
N.A.
53.3
53.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
66.6
N.A.
73.3
80
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
32.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
28
0
0
10
28
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
37
0
0
0
10
0
10
10
10
10
0
0
0
% D
% Glu:
0
0
0
10
82
28
55
0
0
0
0
0
0
0
82
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
10
10
0
10
10
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
28
10
0
10
0
0
0
0
10
0
0
82
91
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
55
0
0
0
% M
% Asn:
0
0
28
0
0
0
0
10
0
19
73
0
10
0
0
% N
% Pro:
91
0
0
82
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
37
28
0
0
28
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
19
0
0
82
0
0
10
0
0
0
% R
% Ser:
0
28
0
10
0
0
0
10
0
0
10
0
10
0
0
% S
% Thr:
0
28
0
0
0
0
0
28
0
37
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
28
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _