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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RNF181
All Species:
32.12
Human Site:
T88
Identified Species:
70.67
UniProt:
Q9P0P0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0P0
NP_057578.1
153
17909
T88
L
E
F
E
E
E
E
T
A
I
E
M
P
C
H
Chimpanzee
Pan troglodytes
XP_515588
153
17865
T88
L
E
F
E
E
E
E
T
A
I
E
M
P
C
H
Rhesus Macaque
Macaca mulatta
XP_001087546
153
17878
T88
L
E
F
E
E
E
E
T
A
I
E
M
P
C
H
Dog
Lupus familis
XP_532978
153
17840
T88
L
E
F
E
E
E
E
T
A
I
E
M
P
C
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY62
165
19082
T100
L
E
F
E
A
E
E
T
V
I
E
M
P
C
H
Rat
Rattus norvegicus
Q6AXU4
165
19269
T100
L
E
F
E
E
E
E
T
V
I
E
M
P
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513994
156
17964
T91
L
E
F
E
E
E
Q
T
A
R
A
M
P
C
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GPV5
156
17823
T91
L
E
F
E
E
G
E
T
V
R
Q
L
P
C
E
Zebra Danio
Brachydanio rerio
Q7ZW78
156
18015
S91
L
E
F
E
E
Q
E
S
V
R
E
M
P
C
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VE61
147
17019
K82
E
P
A
E
E
G
Q
K
Y
R
I
L
P
C
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150472
298
31648
L236
E
G
M
E
Q
G
E
L
T
T
G
L
P
C
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
92.8
N.A.
79.3
81.8
N.A.
69.2
N.A.
67.3
64
N.A.
37.2
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.3
95.4
N.A.
87.2
88.4
N.A.
82
N.A.
80.1
79.4
N.A.
55.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
73.3
N.A.
60
66.6
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
80
N.A.
73.3
80
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
24.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
32.8
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
46
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
82
0
100
82
64
82
0
0
0
64
0
0
0
10
% E
% Phe:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
28
0
0
0
0
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% H
% Ile:
0
0
0
0
0
0
0
0
0
55
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
19
% K
% Leu:
82
0
0
0
0
0
0
10
0
0
0
28
0
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
73
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
100
0
0
% P
% Gln:
0
0
0
0
10
10
19
0
0
0
10
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
37
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
73
10
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
37
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _