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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNF181 All Species: 35.35
Human Site: Y152 Identified Species: 77.78
UniProt: Q9P0P0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0P0 NP_057578.1 153 17909 Y152 E N L H G A M Y T _ _ _ _ _ _
Chimpanzee Pan troglodytes XP_515588 153 17865 Y152 E N L H G A M Y T _ _ _ _ _ _
Rhesus Macaque Macaca mulatta XP_001087546 153 17878 Y152 E N L H G A M Y T _ _ _ _ _ _
Dog Lupus familis XP_532978 153 17840 Y152 E N L H G A M Y T _ _ _ _ _ _
Cat Felis silvestris
Mouse Mus musculus Q9CY62 165 19082 Y164 E N L H G A M Y T _ _ _ _ _ _
Rat Rattus norvegicus Q6AXU4 165 19269 Y164 E N L H G A M Y T _ _ _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513994 156 17964 Y155 E Y L H G A M Y T _ _ _ _ _ _
Chicken Gallus gallus
Frog Xenopus laevis Q6GPV5 156 17823 Y155 E C L H G A M Y T _ _ _ _ _ _
Zebra Danio Brachydanio rerio Q7ZW78 156 18015 Y155 E D L H G A M Y T _ _ _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VE61 147 17019 F146 N T L L D S M F G _ _ _ _ _ _
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150472 298 31648 P290 H S A G G S T P Q L G A P M Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.6 92.8 N.A. 79.3 81.8 N.A. 69.2 N.A. 67.3 64 N.A. 37.2 N.A. N.A. N.A.
Protein Similarity: 100 100 99.3 95.4 N.A. 87.2 88.4 N.A. 82 N.A. 80.1 79.4 N.A. 55.5 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 88.8 N.A. 88.8 88.8 N.A. 22.2 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 88.8 N.A. 88.8 100 N.A. 44.4 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 24.8 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 32.8 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 82 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 91 0 0 0 10 0 10 0 0 0 0 % G
% His: 10 0 0 82 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 91 10 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 91 0 0 0 0 0 0 10 0 % M
% Asn: 10 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 19 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 0 10 0 82 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 82 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 91 91 91 91 91 91 % _