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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM14C All Species: 28.18
Human Site: S56 Identified Species: 51.67
UniProt: Q9P0S9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0S9 NP_057546.1 112 11565 S56 G L G A Y Q L S Q D P R N V W
Chimpanzee Pan troglodytes XP_001167565 114 12030 Y57 G L G A Y Q L Y Q D P R N V W
Rhesus Macaque Macaca mulatta XP_001087705 112 11464 S56 G L G A Y Q L S Q D P R N V W
Dog Lupus familis XP_535885 114 11732 S57 G L G A Y Q L S Q D P R N I W
Cat Felis silvestris
Mouse Mus musculus Q9CQN6 114 11623 S57 G L G A Y Q L S Q D P R N V W
Rat Rattus norvegicus Q924P2 115 11757 S57 G L G A Y Q L S Q D P R N V W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514626 142 14235 S84 G L G A Y Q L S Q D P K N V W
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q0P436 107 10663 D51 G A Y Q T S Q D P G N I W V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1K0 112 11563 L57 Q D T P R P L L Q L G T S L F
Honey Bee Apis mellifera XP_001120404 113 11638 S58 D P T N I G L S I A A T S V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795741 101 10475 L46 M A G Y G A S L T S K N P N D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64847 108 11090 G53 Y V Y T E L P G N P V L A S S
Baker's Yeast Sacchar. cerevisiae P47131 105 11232 R50 G Y L L H M N R D G G L E M A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.4 97.3 86.8 N.A. 85 80 N.A. 59.8 N.A. N.A. 68.7 N.A. 46.4 51.3 N.A. 51.7
Protein Similarity: 100 79.8 98.2 93.8 N.A. 92.9 86 N.A. 67.6 N.A. N.A. 77.6 N.A. 62.5 67.2 N.A. 67.8
P-Site Identity: 100 93.3 100 93.3 N.A. 100 100 N.A. 93.3 N.A. N.A. 13.3 N.A. 13.3 20 N.A. 6.6
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 100 N.A. N.A. 13.3 N.A. 33.3 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 33 25 N.A.
Protein Similarity: N.A. N.A. N.A. 50 43.7 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 54 0 8 0 0 0 8 8 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 8 8 54 0 0 0 0 8 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 70 0 62 0 8 8 0 8 0 16 16 0 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 8 0 0 8 0 8 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % K
% Leu: 0 54 8 8 0 8 70 16 0 8 0 16 0 8 8 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 8 0 0 8 0 8 0 8 8 54 8 0 % N
% Pro: 0 8 0 8 0 8 8 0 8 8 54 0 8 0 0 % P
% Gln: 8 0 0 8 0 54 8 0 62 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 8 0 0 0 47 0 0 0 % R
% Ser: 0 0 0 0 0 8 8 54 0 8 0 0 16 8 16 % S
% Thr: 0 0 16 8 8 0 0 0 8 0 0 16 0 0 0 % T
% Val: 0 8 0 0 0 0 0 0 0 0 8 0 0 62 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 54 % W
% Tyr: 8 8 16 8 54 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _