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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM14C
All Species:
25.15
Human Site:
Y81
Identified Species:
46.11
UniProt:
Q9P0S9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0S9
NP_057546.1
112
11565
Y81
G
I
M
G
M
R
F
Y
H
S
G
K
F
M
P
Chimpanzee
Pan troglodytes
XP_001167565
114
12030
S82
V
G
V
M
G
M
R
S
Y
Y
Y
G
K
F
M
Rhesus Macaque
Macaca mulatta
XP_001087705
112
11464
Y81
G
I
M
G
M
R
F
Y
N
S
G
K
F
M
P
Dog
Lupus familis
XP_535885
114
11732
Y82
G
I
M
G
M
R
F
Y
H
S
G
K
F
M
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQN6
114
11623
Y82
G
I
M
G
M
R
F
Y
N
S
G
K
F
M
P
Rat
Rattus norvegicus
Q924P2
115
11757
Y82
G
I
M
G
M
R
F
Y
N
S
G
K
F
M
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514626
142
14235
Y109
G
V
M
G
M
R
F
Y
N
S
G
K
F
M
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q0P436
107
10663
S76
M
G
K
R
F
Y
N
S
R
K
I
T
P
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W1K0
112
11563
A82
R
S
G
K
L
M
P
A
G
M
V
C
M
L
S
Honey Bee
Apis mellifera
XP_001120404
113
11638
G83
S
G
K
L
M
P
A
G
L
I
A
I
F
S
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795741
101
10475
R71
L
T
G
V
M
G
Y
R
F
S
N
S
G
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64847
108
11090
L78
G
M
M
G
S
R
Y
L
R
T
R
K
V
V
P
Baker's Yeast
Sacchar. cerevisiae
P47131
105
11232
S75
G
V
I
R
G
M
P
S
R
F
T
K
P
V
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
97.3
86.8
N.A.
85
80
N.A.
59.8
N.A.
N.A.
68.7
N.A.
46.4
51.3
N.A.
51.7
Protein Similarity:
100
79.8
98.2
93.8
N.A.
92.9
86
N.A.
67.6
N.A.
N.A.
77.6
N.A.
62.5
67.2
N.A.
67.8
P-Site Identity:
100
0
93.3
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
N.A.
0
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
N.A.
N.A.
0
N.A.
13.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33
25
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
43.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
47
0
8
8
0
0
54
8
8
% F
% Gly:
62
24
16
54
16
8
0
8
8
0
47
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
0
39
8
0
0
0
0
0
0
8
8
8
0
0
0
% I
% Lys:
0
0
16
8
0
0
0
0
0
8
0
62
8
8
0
% K
% Leu:
8
0
0
8
8
0
0
8
8
0
0
0
0
8
0
% L
% Met:
8
8
54
8
62
24
0
0
0
8
0
0
8
47
8
% M
% Asn:
0
0
0
0
0
0
8
0
31
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
16
0
0
0
0
0
16
0
62
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
16
0
54
8
8
24
0
8
0
0
0
0
% R
% Ser:
8
8
0
0
8
0
0
24
0
54
0
8
0
8
8
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
8
8
0
0
0
% T
% Val:
8
16
8
8
0
0
0
0
0
0
8
0
8
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
16
47
8
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _