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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT10
All Species:
12.73
Human Site:
S434
Identified Species:
23.33
UniProt:
Q9P0V9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0V9
NP_653311.1
454
52593
S434
S
E
I
F
H
S
Q
S
F
L
A
T
G
S
N
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
L415
W
E
A
Q
Q
R
I
L
E
Q
Q
N
S
S
R
Rhesus Macaque
Macaca mulatta
XP_001085213
523
60991
S397
M
L
V
P
H
L
T
S
L
N
Q
R
E
F
W
Dog
Lupus familis
XP_540501
432
50596
E373
T
F
K
E
S
E
K
E
L
Q
K
K
F
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8C650
452
52404
S407
C
E
L
F
P
N
Q
S
F
L
A
S
G
S
S
Rat
Rattus norvegicus
Q5PQK1
456
53020
S411
C
E
L
F
P
H
Q
S
F
L
A
S
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510590
457
52831
S427
V
E
T
L
Q
S
Q
S
L
Q
A
T
S
Q
Q
Chicken
Gallus gallus
Q5ZMH1
349
40206
R330
Q
K
E
A
E
L
R
R
M
Q
E
M
I
A
Q
Frog
Xenopus laevis
Q6IRQ5
427
49743
S408
V
A
M
E
T
L
Q
S
Q
S
F
Q
A
T
S
Zebra Danio
Brachydanio rerio
A4FUM1
423
49080
E404
N
R
R
K
V
A
A
E
T
L
Q
S
L
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
K388
R
K
L
E
E
S
R
K
A
L
E
E
D
Y
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790953
437
50335
S405
D
E
Q
R
R
L
L
S
E
E
I
N
L
F
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
E479
A
R
H
K
E
M
K
E
K
L
T
K
Q
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.9
77.6
70
N.A.
81.2
81.5
N.A.
69.1
34.7
70
66.9
N.A.
62.7
N.A.
N.A.
64.9
Protein Similarity:
100
61.2
81.2
82.1
N.A.
90.3
89.9
N.A.
82.7
53.7
81.5
80.4
N.A.
77
N.A.
N.A.
78.8
P-Site Identity:
100
13.3
13.3
0
N.A.
60
60
N.A.
40
0
13.3
6.6
N.A.
13.3
N.A.
N.A.
20
P-Site Similarity:
100
13.3
20
20
N.A.
86.6
80
N.A.
40
20
33.3
26.6
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
8
8
0
8
0
31
0
8
8
0
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
47
8
24
24
8
0
24
16
8
16
8
8
0
0
% E
% Phe:
0
8
0
24
0
0
0
0
24
0
8
0
8
16
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
8
% G
% His:
0
0
8
0
16
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
8
0
0
0
8
0
8
0
0
% I
% Lys:
0
16
8
16
0
0
16
8
8
0
8
16
0
0
8
% K
% Leu:
0
8
24
8
0
31
8
8
24
47
0
0
16
8
8
% L
% Met:
8
0
8
0
0
8
0
0
8
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
8
0
16
0
0
16
% N
% Pro:
0
0
0
8
16
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
8
16
0
39
0
8
31
24
8
8
16
16
% Q
% Arg:
8
16
8
8
8
8
16
8
0
0
0
8
0
0
8
% R
% Ser:
8
0
0
0
8
24
0
54
0
8
0
24
16
31
24
% S
% Thr:
8
0
8
0
8
0
8
0
8
0
8
16
0
8
0
% T
% Val:
16
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _