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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT10
All Species:
4.55
Human Site:
T193
Identified Species:
8.33
UniProt:
Q9P0V9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0V9
NP_653311.1
454
52593
T193
L
K
T
L
D
L
L
T
M
K
N
L
D
S
K
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
E229
F
P
E
T
D
D
E
E
E
N
K
L
V
K
K
Rhesus Macaque
Macaca mulatta
XP_001085213
523
60991
T193
L
K
T
L
D
L
L
T
M
K
N
L
D
S
K
Dog
Lupus familis
XP_540501
432
50596
I193
K
V
N
I
V
P
L
I
A
K
A
D
T
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C650
452
52404
L230
N
G
A
M
N
G
H
L
P
F
A
V
V
G
S
Rat
Rattus norvegicus
Q5PQK1
456
53020
L234
N
G
A
M
N
G
H
L
P
F
A
V
V
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510590
457
52831
V194
M
K
K
L
D
S
K
V
N
I
I
P
I
I
A
Chicken
Gallus gallus
Q5ZMH1
349
40206
L162
F
G
H
G
L
K
P
L
D
V
E
F
M
K
A
Frog
Xenopus laevis
Q6IRQ5
427
49743
D220
Y
Q
F
P
T
D
D
D
A
V
A
E
I
N
S
Zebra Danio
Brachydanio rerio
A4FUM1
423
49080
L233
N
S
S
M
N
A
H
L
P
F
A
V
I
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
A200
V
E
L
Q
R
F
K
A
K
I
I
Q
E
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790953
437
50335
P196
D
S
K
V
N
I
I
P
V
I
A
K
A
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
F271
L
K
P
L
D
L
K
F
M
Q
S
V
Y
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.9
77.6
70
N.A.
81.2
81.5
N.A.
69.1
34.7
70
66.9
N.A.
62.7
N.A.
N.A.
64.9
Protein Similarity:
100
61.2
81.2
82.1
N.A.
90.3
89.9
N.A.
82.7
53.7
81.5
80.4
N.A.
77
N.A.
N.A.
78.8
P-Site Identity:
100
20
100
13.3
N.A.
0
0
N.A.
20
0
0
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
20
100
20
N.A.
20
20
N.A.
26.6
0
13.3
26.6
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
8
0
8
16
0
47
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
39
16
8
8
8
0
0
8
16
8
0
% D
% Glu:
0
8
8
0
0
0
8
8
8
0
8
8
8
8
0
% E
% Phe:
16
0
8
0
0
8
0
8
0
24
0
8
0
0
0
% F
% Gly:
0
24
0
8
0
16
0
0
0
0
0
0
0
24
0
% G
% His:
0
0
8
0
0
0
24
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
8
8
0
24
16
0
24
16
0
% I
% Lys:
8
31
16
0
0
8
24
0
8
24
8
8
0
16
31
% K
% Leu:
24
0
8
31
8
24
24
31
0
0
0
24
0
8
0
% L
% Met:
8
0
0
24
0
0
0
0
24
0
0
0
8
0
0
% M
% Asn:
24
0
8
0
31
0
0
0
8
8
16
0
0
8
8
% N
% Pro:
0
8
8
8
0
8
8
8
24
0
0
8
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
8
0
0
8
0
0
0
0
8
0
0
16
39
% S
% Thr:
0
0
16
8
8
0
0
16
0
0
0
0
8
0
8
% T
% Val:
8
8
0
8
8
0
0
8
8
16
0
31
24
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _