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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEPT10
All Species:
11.82
Human Site:
Y177
Identified Species:
21.67
UniProt:
Q9P0V9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P0V9
NP_653311.1
454
52593
Y177
S
R
I
H
V
C
L
Y
F
I
S
P
T
G
H
Chimpanzee
Pan troglodytes
Q5R1W1
434
50272
Q213
K
Q
I
M
K
E
I
Q
E
H
K
I
K
I
Y
Rhesus Macaque
Macaca mulatta
XP_001085213
523
60991
Y177
S
R
I
H
V
C
L
Y
F
I
S
P
T
G
H
Dog
Lupus familis
XP_540501
432
50596
L177
H
S
L
K
S
L
D
L
L
T
M
K
N
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8C650
452
52404
T214
V
Q
I
Y
Q
F
P
T
D
D
D
T
T
S
K
Rat
Rattus norvegicus
Q5PQK1
456
53020
T218
V
Q
I
Y
Q
F
P
T
D
D
D
T
T
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510590
457
52831
S178
F
I
T
P
T
G
H
S
L
K
S
L
D
L
V
Chicken
Gallus gallus
Q5ZMH1
349
40206
H146
H
I
I
D
N
R
V
H
C
C
F
Y
F
I
S
Frog
Xenopus laevis
Q6IRQ5
427
49743
E204
F
K
I
K
I
M
S
E
L
V
S
N
G
V
Q
Zebra Danio
Brachydanio rerio
A4FUM1
423
49080
T217
V
Q
I
Y
Q
F
P
T
D
D
E
A
V
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54359
419
48456
I184
K
V
N
I
I
P
V
I
A
K
A
D
T
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790953
437
50335
L180
T
G
H
S
L
K
S
L
D
L
V
T
M
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32457
520
60021
Y255
K
R
I
H
A
C
L
Y
F
I
E
P
T
G
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.9
77.6
70
N.A.
81.2
81.5
N.A.
69.1
34.7
70
66.9
N.A.
62.7
N.A.
N.A.
64.9
Protein Similarity:
100
61.2
81.2
82.1
N.A.
90.3
89.9
N.A.
82.7
53.7
81.5
80.4
N.A.
77
N.A.
N.A.
78.8
P-Site Identity:
100
6.6
100
0
N.A.
13.3
13.3
N.A.
6.6
6.6
13.3
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
6.6
N.A.
26.6
26.6
N.A.
6.6
20
33.3
20
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
8
8
0
16
0
% A
% Cys:
0
0
0
0
0
24
0
0
8
8
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
31
24
16
8
8
0
8
% D
% Glu:
0
0
0
0
0
8
0
8
8
0
16
0
0
0
8
% E
% Phe:
16
0
0
0
0
24
0
0
24
0
8
0
8
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
0
0
8
24
0
% G
% His:
16
0
8
24
0
0
8
8
0
8
0
0
0
0
24
% H
% Ile:
0
16
70
8
16
0
8
8
0
24
0
8
0
31
0
% I
% Lys:
24
8
0
16
8
8
0
0
0
16
8
8
8
8
24
% K
% Leu:
0
0
8
0
8
8
24
16
24
8
0
8
0
8
0
% L
% Met:
0
0
0
8
0
8
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
8
8
0
0
% N
% Pro:
0
0
0
8
0
8
24
0
0
0
0
24
0
0
0
% P
% Gln:
0
31
0
0
24
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
0
24
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
16
8
0
8
8
0
16
8
0
0
31
0
0
8
16
% S
% Thr:
8
0
8
0
8
0
0
24
0
8
0
24
47
0
0
% T
% Val:
24
8
0
0
16
0
16
0
0
8
8
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
24
0
0
0
24
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _