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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIPOX All Species: 25.15
Human Site: S121 Identified Species: 42.56
UniProt: Q9P0Z9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0Z9 NP_057602.2 390 44066 S121 R V E H Q C L S S E E L K Q R
Chimpanzee Pan troglodytes XP_511370 390 44059 S121 R V E H Q C L S S E E L K Q R
Rhesus Macaque Macaca mulatta XP_001110686 390 44143 S121 R V E H Q C L S S E E L K Q R
Dog Lupus familis XP_548297 392 44194 S121 R V E H Q Y F S A E E L K Q R
Cat Felis silvestris
Mouse Mus musculus Q9D826 390 43828 S121 G I D H E Y L S S V D L K Q R
Rat Rattus norvegicus NP_001012009 390 43872 S121 G I D H E C L S S V H L K Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510684 393 42970 P125 G V A H Q A L P P E E L R R H
Chicken Gallus gallus
Frog Xenopus laevis NP_001090110 393 43945 S122 Q I P W E S L S P A E M K L R
Zebra Danio Brachydanio rerio XP_686922 508 56721 E240 K I P T V F L E K Q E F N E H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18006 384 43105 T118 K H E V I K G T E V G K R Y P
Sea Urchin Strong. purpuratus XP_001191641 357 40280 F103 H E P H Y S S F I D K A A G V
Poplar Tree Populus trichocarpa XP_002324381 411 45180 D121 S L P H Q V L D G Q Q V A D R
Maize Zea mays NP_001149835 415 43797 S125 E V V A G D E S S S W P W A G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJA7 416 45683 D122 G L A H R V M D S H A V S E H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 94.8 83.4 N.A. 81 79.7 N.A. 69.2 N.A. 60.3 40.5 N.A. N.A. N.A. 35.6 42.5
Protein Similarity: 100 99.7 97.4 90.5 N.A. 85.9 86.1 N.A. 80.9 N.A. 73.7 55.9 N.A. N.A. N.A. 57.1 58.9
P-Site Identity: 100 100 100 80 N.A. 53.3 60 N.A. 46.6 N.A. 33.3 13.3 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 80 80 N.A. 60 N.A. 60 40 N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: 37.7 31.8 N.A. 33.6 N.A. N.A.
Protein Similarity: 54.5 52.7 N.A. 52.8 N.A. N.A.
P-Site Identity: 26.6 20 N.A. 13.3 N.A. N.A.
P-Site Similarity: 53.3 20 N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 8 0 8 0 0 8 8 8 8 15 8 0 % A
% Cys: 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 0 0 8 0 15 0 8 8 0 0 8 0 % D
% Glu: 8 8 36 0 22 0 8 8 8 36 50 0 0 15 0 % E
% Phe: 0 0 0 0 0 8 8 8 0 0 0 8 0 0 0 % F
% Gly: 29 0 0 0 8 0 8 0 8 0 8 0 0 8 8 % G
% His: 8 8 0 72 0 0 0 0 0 8 8 0 0 0 22 % H
% Ile: 0 29 0 0 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 15 0 0 0 0 8 0 0 8 0 8 8 50 0 0 % K
% Leu: 0 15 0 0 0 0 65 0 0 0 0 50 0 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 29 0 0 0 0 8 15 0 0 8 0 0 8 % P
% Gln: 8 0 0 0 43 0 0 0 0 15 8 0 0 43 0 % Q
% Arg: 29 0 0 0 8 0 0 0 0 0 0 0 15 8 58 % R
% Ser: 8 0 0 0 0 15 8 58 50 8 0 0 8 0 0 % S
% Thr: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 43 8 8 8 15 0 0 0 22 0 15 0 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 8 0 8 0 0 % W
% Tyr: 0 0 0 0 8 15 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _