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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIPOX All Species: 27.58
Human Site: S380 Identified Species: 46.67
UniProt: Q9P0Z9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0Z9 NP_057602.2 390 44066 S380 D L A P F R I S R F P S L G K
Chimpanzee Pan troglodytes XP_511370 390 44059 S380 D L A P F R I S R F P S L G K
Rhesus Macaque Macaca mulatta XP_001110686 390 44143 S380 D L A P F R I S R F P S L G K
Dog Lupus familis XP_548297 392 44194 S382 D L T P F R M S R F P G L G K
Cat Felis silvestris
Mouse Mus musculus Q9D826 390 43828 S380 D L A P F R M S R F S T L S K
Rat Rattus norvegicus NP_001012009 390 43872 S380 D L A P F R I S R F S K L S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510684 393 42970 S383 D L A P F R I S R F C G P G K
Chicken Gallus gallus
Frog Xenopus laevis NP_001090110 393 43945 S383 D L K P F R I S R F K T P L K
Zebra Danio Brachydanio rerio XP_686922 508 56721 Q498 D L S P F R I Q R F Q S Q S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18006 384 43105 F373 K T T V D V S F F S A N R F K
Sea Urchin Strong. purpuratus XP_001191641 357 40280 R340 D I S P C S L R R F N N S A L
Poplar Tree Populus trichocarpa XP_002324381 411 45180 I386 V D L K H F R I Q R F Q E N P
Maize Zea mays NP_001149835 415 43797 L394 A A E A G V D L R P L T I G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJA7 416 45683 F388 G G V E M K Q F S L R R F E D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 94.8 83.4 N.A. 81 79.7 N.A. 69.2 N.A. 60.3 40.5 N.A. N.A. N.A. 35.6 42.5
Protein Similarity: 100 99.7 97.4 90.5 N.A. 85.9 86.1 N.A. 80.9 N.A. 73.7 55.9 N.A. N.A. N.A. 57.1 58.9
P-Site Identity: 100 100 100 80 N.A. 73.3 80 N.A. 80 N.A. 66.6 66.6 N.A. N.A. N.A. 6.6 26.6
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 80 N.A. 80 N.A. 73.3 73.3 N.A. N.A. N.A. 13.3 53.3
Percent
Protein Identity: 37.7 31.8 N.A. 33.6 N.A. N.A.
Protein Similarity: 54.5 52.7 N.A. 52.8 N.A. N.A.
P-Site Identity: 0 13.3 N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 33.3 N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 43 8 0 0 0 0 0 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 72 8 0 0 8 0 8 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 8 8 0 0 0 0 0 0 0 0 8 8 0 % E
% Phe: 0 0 0 0 65 8 0 15 8 72 8 0 8 8 0 % F
% Gly: 8 8 0 0 8 0 0 0 0 0 0 15 0 43 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 50 8 0 0 0 0 8 0 0 % I
% Lys: 8 0 8 8 0 8 0 0 0 0 8 8 0 0 72 % K
% Leu: 0 65 8 0 0 0 8 8 0 8 8 0 43 8 8 % L
% Met: 0 0 0 0 8 0 15 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 15 0 8 0 % N
% Pro: 0 0 0 72 0 0 0 0 0 8 29 0 15 0 8 % P
% Gln: 0 0 0 0 0 0 8 8 8 0 8 8 8 0 0 % Q
% Arg: 0 0 0 0 0 65 8 8 79 8 8 8 8 0 8 % R
% Ser: 0 0 15 0 0 8 8 58 8 8 15 29 8 22 0 % S
% Thr: 0 8 15 0 0 0 0 0 0 0 0 22 0 0 0 % T
% Val: 8 0 8 8 0 15 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _