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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIPOX All Species: 25.45
Human Site: Y372 Identified Species: 43.08
UniProt: Q9P0Z9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9P0Z9 NP_057602.2 390 44066 Y372 S M K L T P S Y D L A P F R I
Chimpanzee Pan troglodytes XP_511370 390 44059 Y372 S M K L T P S Y D L A P F R I
Rhesus Macaque Macaca mulatta XP_001110686 390 44143 Y372 S M K L T P S Y D L A P F R I
Dog Lupus familis XP_548297 392 44194 Y374 S M K L T P S Y D L T P F R M
Cat Felis silvestris
Mouse Mus musculus Q9D826 390 43828 Y372 S M K L P P S Y D L A P F R M
Rat Rattus norvegicus NP_001012009 390 43872 Y372 S M K L P P S Y D L A P F R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510684 393 42970 Q375 S L G M D P S Q D L A P F R I
Chicken Gallus gallus
Frog Xenopus laevis NP_001090110 393 43945 Y375 C I G E K Q S Y D L K P F R I
Zebra Danio Brachydanio rerio XP_686922 508 56721 H490 A M G Q V P S H D L S P F R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18006 384 43105 K365 L A E M A A G K K T T V D V S
Sea Urchin Strong. purpuratus XP_001191641 357 40280 H332 A L G K T P S H D I S P C S L
Poplar Tree Populus trichocarpa XP_002324381 411 45180 G378 A L S G E A K G V D L K H F R
Maize Zea mays NP_001149835 415 43797 T386 A L D G E A S T A A E A G V D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJA7 416 45683 G380 A M E V E A G G G G V E M K Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 94.8 83.4 N.A. 81 79.7 N.A. 69.2 N.A. 60.3 40.5 N.A. N.A. N.A. 35.6 42.5
Protein Similarity: 100 99.7 97.4 90.5 N.A. 85.9 86.1 N.A. 80.9 N.A. 73.7 55.9 N.A. N.A. N.A. 57.1 58.9
P-Site Identity: 100 100 100 86.6 N.A. 86.6 93.3 N.A. 66.6 N.A. 53.3 60 N.A. N.A. N.A. 0 33.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 80 N.A. 60 80 N.A. N.A. N.A. 13.3 73.3
Percent
Protein Identity: 37.7 31.8 N.A. 33.6 N.A. N.A.
Protein Similarity: 54.5 52.7 N.A. 52.8 N.A. N.A.
P-Site Identity: 0 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 20 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 36 8 0 0 8 29 0 0 8 8 43 8 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 0 8 0 0 0 72 8 0 0 8 0 8 % D
% Glu: 0 0 15 8 22 0 0 0 0 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 65 8 0 % F
% Gly: 0 0 29 15 0 0 15 15 8 8 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 15 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 50 % I
% Lys: 0 0 43 8 8 0 8 8 8 0 8 8 0 8 0 % K
% Leu: 8 29 0 43 0 0 0 0 0 65 8 0 0 0 8 % L
% Met: 0 58 0 15 0 0 0 0 0 0 0 0 8 0 15 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 15 65 0 0 0 0 0 72 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 8 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 65 8 % R
% Ser: 50 0 8 0 0 0 79 0 0 0 15 0 0 8 8 % S
% Thr: 0 0 0 0 36 0 0 8 0 8 15 0 0 0 0 % T
% Val: 0 0 0 8 8 0 0 0 8 0 8 8 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _