KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOK5
All Species:
22.73
Human Site:
S18
Identified Species:
62.5
UniProt:
Q9P104
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P104
NP_060901.2
306
35464
S18
Q
G
Y
V
R
I
R
S
R
R
L
G
I
Y
Q
Chimpanzee
Pan troglodytes
XP_001169624
307
35639
S18
Q
G
Y
V
R
I
R
S
R
R
L
G
I
Y
Q
Rhesus Macaque
Macaca mulatta
XP_001091477
306
35443
S18
Q
G
Y
V
R
I
R
S
R
R
L
G
I
Y
Q
Dog
Lupus familis
XP_543060
376
42722
G88
E
G
R
R
Q
E
H
G
F
V
E
S
I
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZM9
306
35435
S18
Q
G
Y
V
R
I
R
S
R
R
L
G
I
Y
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509626
297
34314
I13
E
E
D
I
G
D
A
I
Y
Q
R
C
W
L
V
Chicken
Gallus gallus
A3R064
426
47148
W22
C
K
F
G
K
R
T
W
R
K
I
R
A
Q
L
Frog
Xenopus laevis
NP_001080630
320
36761
S18
Q
G
Y
V
R
M
K
S
R
K
L
G
I
Y
R
Zebra Danio
Brachydanio rerio
NP_001082908
332
38492
S18
Q
G
Y
V
R
I
R
S
K
K
L
G
I
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
99.3
76.5
N.A.
98.3
N.A.
N.A.
87.9
21.3
52.8
61.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
100
79.5
N.A.
99
N.A.
N.A.
92.1
35.2
69.6
78.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
26.6
N.A.
100
N.A.
N.A.
0
6.6
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
N.A.
N.A.
20
33.3
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
23
12
0
0
0
12
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
12
0
0
0
0
12
0
% F
% Gly:
0
78
0
12
12
0
0
12
0
0
0
67
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
56
0
12
0
0
12
0
78
0
0
% I
% Lys:
0
12
0
0
12
0
12
0
12
34
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
67
0
0
12
12
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
67
0
0
0
12
0
0
0
0
12
0
0
0
12
56
% Q
% Arg:
0
0
12
12
67
12
56
0
67
45
12
12
0
0
23
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
67
0
0
0
0
0
12
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% W
% Tyr:
0
0
67
0
0
0
0
0
12
0
0
0
0
67
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _