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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R1L
All Species:
12.73
Human Site:
T431
Identified Species:
25.45
UniProt:
Q9P1A2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1A2
NP_001035847
438
49554
T431
K
R
R
N
I
I
D
T
A
V
L
E
K
Q
N
Chimpanzee
Pan troglodytes
XP_001138009
932
104418
D923
A
S
T
K
I
S
E
D
A
M
S
T
A
S
S
Rhesus Macaque
Macaca mulatta
XP_001087863
964
107735
T957
K
R
R
N
I
I
D
T
A
V
L
E
K
Q
N
Dog
Lupus familis
XP_534465
1000
111859
T993
K
R
R
S
T
A
D
T
R
V
L
E
E
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2V1
951
106280
D942
S
S
T
K
L
S
E
D
A
M
S
T
A
S
S
Rat
Rattus norvegicus
Q8VI02
951
105597
D942
S
S
T
K
L
S
E
D
A
M
S
T
A
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510959
970
109729
T963
N
Q
N
I
I
N
T
T
A
L
E
K
Q
S
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956554
913
102846
D904
A
N
T
R
L
N
E
D
A
M
S
T
T
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P36179
591
65405
E554
Q
K
I
S
P
F
L
E
A
S
V
I
D
A
Q
Honey Bee
Apis mellifera
XP_001122271
787
90110
S774
N
S
V
L
D
I
L
S
Q
T
K
T
E
Q
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782078
936
105410
Y929
S
G
D
T
K
V
H
Y
A
E
G
E
L
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P31383
635
70933
I517
S
D
W
C
R
D
E
I
I
S
R
L
L
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.2
42.6
38.2
N.A.
32.8
32.4
N.A.
39.1
N.A.
N.A.
31.5
N.A.
20.8
26
N.A.
25.8
Protein Similarity:
100
39.8
44.5
41.9
N.A.
39.1
38.7
N.A.
42.3
N.A.
N.A.
38.8
N.A.
36.2
37.7
N.A.
35
P-Site Identity:
100
13.3
100
66.6
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
6.6
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
33.3
100
80
N.A.
33.3
33.3
N.A.
46.6
N.A.
N.A.
33.3
N.A.
33.3
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
9
0
0
75
0
0
0
25
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
9
9
25
34
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
42
9
0
9
9
34
17
0
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
9
34
25
0
9
9
0
0
9
0
0
0
% I
% Lys:
25
9
0
25
9
0
0
0
0
0
9
9
17
9
0
% K
% Leu:
0
0
0
9
25
0
17
0
0
9
25
9
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% M
% Asn:
17
9
9
17
0
17
0
0
0
0
0
0
0
0
25
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
9
9
0
0
0
0
0
0
9
0
0
0
9
34
9
% Q
% Arg:
0
25
25
9
9
0
0
0
9
0
9
0
0
0
0
% R
% Ser:
34
34
0
17
0
25
0
9
0
17
34
0
0
42
42
% S
% Thr:
0
0
34
9
9
0
9
34
0
9
0
42
9
0
0
% T
% Val:
0
0
9
0
0
9
0
0
0
25
9
0
0
0
9
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _