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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS54
All Species:
20.3
Human Site:
S519
Identified Species:
37.22
UniProt:
Q9P1Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1Q0
NP_001005739.1
977
110589
S519
I
H
E
G
M
F
I
S
D
A
F
G
E
G
E
Chimpanzee
Pan troglodytes
XP_001165146
977
110528
S519
I
H
E
G
M
F
I
S
D
A
F
G
E
G
E
Rhesus Macaque
Macaca mulatta
XP_001087667
977
110603
S519
I
H
E
G
M
F
I
S
D
A
F
G
E
G
E
Dog
Lupus familis
XP_531846
977
110860
S519
I
H
E
G
M
F
I
S
D
A
F
N
E
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SPW0
977
110378
S519
T
H
E
G
W
F
I
S
D
A
F
S
E
G
E
Rat
Rattus norvegicus
Q9JMK8
965
108823
S507
T
H
E
G
L
F
I
S
D
A
F
S
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511329
978
110848
D520
H
E
G
M
F
I
S
D
A
F
N
E
G
E
K
Chicken
Gallus gallus
XP_419349
979
111040
F521
Y
L
T
H
E
G
M
F
I
S
D
A
F
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124248
998
112046
F539
Y
L
T
H
E
G
L
F
I
S
D
A
L
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLC0
940
105223
D490
I
E
V
L
A
R
S
D
S
D
Q
E
I
S
L
Honey Bee
Apis mellifera
XP_001121762
883
100031
V456
K
E
E
A
V
T
T
V
R
A
V
T
K
Q
R
Nematode Worm
Caenorhab. elegans
Q22639
1058
119163
D610
I
H
E
S
E
S
D
D
E
V
G
T
T
F
S
Sea Urchin
Strong. purpuratus
XP_790678
943
106615
E487
M
I
L
L
T
R
I
E
K
L
V
N
M
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
96.5
N.A.
92.6
89.9
N.A.
90.8
86.5
N.A.
67.3
N.A.
24.1
36.5
21
48.8
Protein Similarity:
100
99.9
99.6
98
N.A.
96.3
94.2
N.A.
94.6
93.5
N.A.
81.8
N.A.
42.5
54.1
42.2
67
P-Site Identity:
100
100
100
86.6
N.A.
80
73.3
N.A.
0
13.3
N.A.
0
N.A.
6.6
13.3
20
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
6.6
26.6
N.A.
20
N.A.
6.6
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
8
54
0
16
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
24
47
8
16
0
0
0
8
% D
% Glu:
0
24
62
0
24
0
0
8
8
0
0
16
47
8
54
% E
% Phe:
0
0
0
0
8
47
0
16
0
8
47
0
8
8
0
% F
% Gly:
0
0
8
47
0
16
0
0
0
0
8
24
8
39
0
% G
% His:
8
54
0
16
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
47
8
0
0
0
8
54
0
16
0
0
0
8
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% K
% Leu:
0
16
8
16
8
0
8
0
0
8
0
0
8
0
8
% L
% Met:
8
0
0
8
31
0
8
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
16
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
16
0
0
8
0
0
0
0
0
8
% R
% Ser:
0
0
0
8
0
8
16
47
8
16
0
16
0
16
8
% S
% Thr:
16
0
16
0
8
8
8
0
0
0
0
16
8
0
0
% T
% Val:
0
0
8
0
8
0
0
8
0
8
16
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _