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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS54
All Species:
18.79
Human Site:
S570
Identified Species:
34.44
UniProt:
Q9P1Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1Q0
NP_001005739.1
977
110589
S570
S
S
K
E
H
T
S
S
S
A
I
P
G
G
V
Chimpanzee
Pan troglodytes
XP_001165146
977
110528
S570
S
S
K
E
H
T
S
S
S
A
I
P
G
G
A
Rhesus Macaque
Macaca mulatta
XP_001087667
977
110603
S570
S
S
K
E
H
T
S
S
S
A
I
P
G
G
V
Dog
Lupus familis
XP_531846
977
110860
S570
S
S
K
E
Q
T
S
S
S
A
T
P
G
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5SPW0
977
110378
A570
S
S
K
E
Q
T
S
A
C
A
P
P
G
G
I
Rat
Rattus norvegicus
Q9JMK8
965
108823
A558
S
S
K
E
Q
T
P
A
S
A
T
L
G
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511329
978
110848
S571
S
S
K
E
H
A
T
S
S
L
T
P
G
G
V
Chicken
Gallus gallus
XP_419349
979
111040
S572
S
S
S
S
K
E
P
S
S
V
T
P
G
G
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124248
998
112046
N590
S
S
R
E
H
N
S
N
T
T
S
C
L
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLC0
940
105223
A541
V
G
I
M
Q
Q
T
A
D
A
A
V
G
A
Q
Honey Bee
Apis mellifera
XP_001121762
883
100031
L507
I
Q
S
L
T
F
L
L
M
R
V
K
A
V
H
Nematode Worm
Caenorhab. elegans
Q22639
1058
119163
E661
H
V
L
P
L
I
A
E
F
G
H
Q
C
A
Q
Sea Urchin
Strong. purpuratus
XP_790678
943
106615
I538
D
D
E
R
L
A
E
I
E
E
C
M
E
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
96.5
N.A.
92.6
89.9
N.A.
90.8
86.5
N.A.
67.3
N.A.
24.1
36.5
21
48.8
Protein Similarity:
100
99.9
99.6
98
N.A.
96.3
94.2
N.A.
94.6
93.5
N.A.
81.8
N.A.
42.5
54.1
42.2
67
P-Site Identity:
100
93.3
100
86.6
N.A.
66.6
66.6
N.A.
73.3
53.3
N.A.
40
N.A.
13.3
0
0
0
P-Site Similarity:
100
93.3
100
86.6
N.A.
80
73.3
N.A.
80
53.3
N.A.
60
N.A.
26.6
6.6
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
8
24
0
54
8
0
8
24
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
8
8
8
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
8
62
0
8
8
8
8
8
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
8
0
0
70
62
0
% G
% His:
8
0
0
0
39
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
8
0
8
0
0
8
0
8
0
0
24
0
0
0
8
% I
% Lys:
0
0
54
0
8
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
8
8
16
0
8
8
0
8
0
8
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
16
0
0
0
8
54
0
8
0
% P
% Gln:
0
8
0
0
31
8
0
0
0
0
0
8
0
0
16
% Q
% Arg:
0
0
8
8
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
70
70
16
8
0
0
47
47
54
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
47
16
0
8
8
31
0
0
0
0
% T
% Val:
8
8
0
0
0
0
0
0
0
8
8
8
0
8
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _