KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS54
All Species:
26.67
Human Site:
S582
Identified Species:
48.89
UniProt:
Q9P1Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P1Q0
NP_001005739.1
977
110589
S582
G
G
V
D
I
M
V
S
E
D
M
K
L
T
D
Chimpanzee
Pan troglodytes
XP_001165146
977
110528
S582
G
G
A
D
I
M
V
S
E
D
M
K
L
T
D
Rhesus Macaque
Macaca mulatta
XP_001087667
977
110603
S582
G
G
V
D
I
M
V
S
E
D
M
K
L
T
D
Dog
Lupus familis
XP_531846
977
110860
N582
G
G
V
D
I
M
V
N
E
D
M
K
L
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5SPW0
977
110378
S582
G
G
I
E
I
I
V
S
E
D
M
R
L
T
D
Rat
Rattus norvegicus
Q9JMK8
965
108823
S570
G
G
V
D
I
I
V
S
E
D
M
R
L
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511329
978
110848
S583
G
G
V
D
L
M
F
S
E
D
V
K
L
T
D
Chicken
Gallus gallus
XP_419349
979
111040
S584
G
G
V
E
M
M
I
S
D
D
M
K
L
T
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124248
998
112046
L602
L
P
V
G
A
A
A
L
E
D
V
M
P
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLC0
940
105223
L553
G
A
Q
D
A
V
N
L
I
D
S
E
A
F
L
Honey Bee
Apis mellifera
XP_001121762
883
100031
D519
A
V
H
D
V
M
R
D
T
V
D
L
A
A
G
Nematode Worm
Caenorhab. elegans
Q22639
1058
119163
R673
C
A
Q
Q
R
I
S
R
L
L
I
A
R
A
K
Sea Urchin
Strong. purpuratus
XP_790678
943
106615
Q550
E
A
E
A
I
L
P
Q
G
D
F
L
I
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
96.5
N.A.
92.6
89.9
N.A.
90.8
86.5
N.A.
67.3
N.A.
24.1
36.5
21
48.8
Protein Similarity:
100
99.9
99.6
98
N.A.
96.3
94.2
N.A.
94.6
93.5
N.A.
81.8
N.A.
42.5
54.1
42.2
67
P-Site Identity:
100
93.3
100
93.3
N.A.
73.3
86.6
N.A.
80
66.6
N.A.
26.6
N.A.
20
13.3
0
13.3
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
100
N.A.
40
N.A.
33.3
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
8
8
16
8
8
0
0
0
0
8
16
24
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
62
0
0
0
8
8
85
8
0
0
0
62
% D
% Glu:
8
0
8
16
0
0
0
0
62
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% F
% Gly:
70
62
0
8
0
0
0
0
8
0
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
54
24
8
0
8
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
8
% K
% Leu:
8
0
0
0
8
8
0
16
8
8
0
16
62
0
8
% L
% Met:
0
0
0
0
8
54
0
0
0
0
54
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
0
0
0
0
8
0
8
% P
% Gln:
0
0
16
8
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
8
0
0
0
16
8
0
0
% R
% Ser:
0
0
0
0
0
0
8
54
0
0
8
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
0
0
0
62
0
% T
% Val:
0
8
54
0
8
8
47
0
0
8
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _